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CD9 Knockout Cell Lines

Gene: CD9

Official Full Name: CD9 moleculeprovided by HGNC

Gene Summary: This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00135 CD9 Knockout cell line (U-87 MG) Human CD9 1:3~1:4 Negative Online Inquiry
KO00516 CD9 Knockout cell line (HEK293) Human CD9 1:3~1:6 Negative Online Inquiry
KO06134 CD9 Knockout cell line (HeLa) Human CD9 1:3~1:6 Negative Online Inquiry
KO06135 CD9 Knockout cell line (HCT 116) Human CD9 1:2~1:4 Negative Online Inquiry
KO06136 CD9 Knockout cell line (A549) Human CD9 1:3~1:4 Negative Online Inquiry

Background

CD9 Gene Knockout Cell Lines are highly specialized cellular models engineered to lack the CD9 gene, a member of the tetraspanin family known to play crucial roles in cell adhesion, migration, and intracellular signaling. These cell lines provide a novel platform for studying the functional impacts of CD9 in various biological processes, including cancer progression, immune response modulation, and tissue repair mechanisms.

The key functions of these knockout cell lines revolve around their ability to elucidate the specific role of CD9 in cell behavior. By observing the differences in cellular dynamics—such as motility, proliferation, and signaling pathways—researchers can gain deep insights into the molecular pathways influenced by CD9. This understanding is particularly significant in cancer research, where CD9 expression is often associated with metastasis and poor prognosis, as well as in immunology, where it is implicated in the activation and differentiation of immune cells.

In research and clinical settings, CD9 Gene Knockout Cell Lines serve as invaluable tools for drug discovery, biomarker identification, and therapeutic development. Their deployment can accelerate the characterization of CD9 as a potential therapeutic target, providing critical information that may lead to novel treatment strategies for various diseases.

One distinct advantage these cell lines offer is their specificity to CD9, which allows for controlled experiments that minimize confounding factors associated with other tetraspanins. Unlike alternative methods, such as transient RNA interference or overexpression systems, these knockout lines ensure stable gene disruption, leading to reproducible results across experiments.

For researchers, clinicians, and pharmaceutical developers, the value of CD9 Gene Knockout Cell Lines lies in their ability to streamline research processes and uncover actionable insights that can be translated into clinical applications. As a leader in biological product innovation, our company remains committed to providing high-quality research tools that empower advancements in health and medicine, ensuring our clients can achieve their research objectives with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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