PRDM16 Knockout cell line (293T)

Catalog Number: KOA01610

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Specifications

Product Information
Product Name	PRDM16 Knockout cell line (293T)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:6
species	Human
Gene	PRDM16
Gene ID	63976
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10%FBS
Parental Cell Line	293T
Quality Control	Genotype: PRDM16 Knockout cell line (293T)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	PR/SET domain 16provided by HGNC
Also known as	MEL1; KMT8F; LVNC8; PFM13; CMD1LL
Gene Description	The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Expression	Broad expression in stomach (RPKM 3.4), thyroid (RPKM 3.1) and 17 other tissues See more

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