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NAGLU Knockout cell line (U-2932)

Catalog Number: KOA45537

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Specifications

Product Information
Product Name NAGLU Knockout cell line (U-2932)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Human Lymphocyte-like, suspension
Passage ratio 1:2-1:4
species Human
Gene NAGLU
Gene ID 4669
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line U-2932
Quality Control Genotype: NAGLU Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name N-acetyl-alpha-glucosaminidaseprovided by HGNC
Also known as NAG; CMT2V; MPS3B; UFHSD; MPS-IIIB
Gene Description This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008]
Expression Ubiquitous expression in kidney (RPKM 14.8), fat (RPKM 12.3) and 25 other tissues See more

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