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MMP3 Knockout cell line (NCM460)

Catalog Number: KOA76479

Price: Online Inquiry

Specifications Downloads Related products

Specifications

Product Information
Product Name MMP3 Knockout cell line (NCM460)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adheren
Passage ratio 1:2~1:3
species Human
Gene MMP3
Gene ID 4314
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line NCM460
Quality Control Genotype: MMP3 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name matrix metallopeptidase 3provided by HGNC
Also known as SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
Gene Description Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Expression Biased expression in endometrium (RPKM 37.5), appendix (RPKM 12.3) and 1 other tissue See more

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