MGMT Knockout cell line (U-2932)

Name: MGMT Knockout cell line (U-2932)
Brand: CD Biosynsis
SKU: KOA45696
Availability: InStock

Catalog Number: KOA45696

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Specifications

Product Information
Product Name	MGMT Knockout cell line (U-2932)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Human Lymphocyte-like, suspension
Passage ratio	1：2-1：4
species	Human
Gene	MGMT
Gene ID	4255
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	U-2932
Quality Control	Genotype: MGMT Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	O-6-methylguanine-DNA methyltransferaseprovided by HGNC
Gene Description	Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
Expression	Ubiquitous expression in liver (RPKM 6.2), kidney (RPKM 3.0) and 25 other tissues See more

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