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GABRB3 Knockout cell line (U-2932)

Catalog Number: KOA46682

Price: Online Inquiry

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Specifications

Product Information
Product Name GABRB3 Knockout cell line (U-2932)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Human Lymphocyte-like, suspension
Passage ratio 1:2-1:4
species Human
Gene GABRB3
Gene ID 2562
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line U-2932
Quality Control Genotype: GABRB3 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name gamma-aminobutyric acid type A receptor subunit beta3provided by HGNC
Also known as ECA5; DEE43; EIEE43
Gene Description This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
Expression Biased expression in brain (RPKM 22.9), gall bladder (RPKM 6.3) and 7 other tissues See more

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