BRD2 Knockout cell line (TPC-1)

Catalog Number: KOA60137

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Specifications

Product Information
Product Name	BRD2 Knockout cell line (TPC-1)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:5-1:8
species	Human
Gene	BRD2
Gene ID	6046
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%DMEM+10%FBS
Parental Cell Line	TPC-1
Quality Control	Genotype: BRD2 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	bromodomain containing 2provided by HGNC
Also known as	FSH; NAT; RNF3; FSRG1; RING3; FSHRG1; D6S113E; O27.1.1; BRD2-IT1
Gene Description	This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Expression	Ubiquitous expression in bone marrow (RPKM 74.5), thyroid (RPKM 55.5) and 25 other tissues See more

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