ATG4D Knockout cell line (293T)

Catalog Number: KOA00072

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Specifications

Product Information
Product Name	ATG4D Knockout cell line (293T)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:6
species	Human
Gene	ATG4D
Gene ID	84971
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10%FBS
Parental Cell Line	293T
Quality Control	Genotype: ATG4D Knockout cell line (293T)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	autophagy related 4D cysteine peptidaseprovided by HGNC
Also known as	APG4D; AUTL4; APG4-D; HsAPG4D
Gene Description	Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Expression	Broad expression in testis (RPKM 21.1), duodenum (RPKM 13.4) and 25 other tissues See more

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