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ZYG11A Knockout Cell Lines

Gene: ZYG11A

Official Full Name: zyg-11 family member A, cell cycle regulatorprovided by HGNC

Gene Summary: Predicted to be part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11839 ZYG11A Knockout cell line (HeLa) Human ZYG11A 1:3~1:6 Negative Online Inquiry
KO11840 ZYG11A Knockout cell line (HEK293) Human ZYG11A 1:3~1:6 Negative Online Inquiry
KO11841 ZYG11A Knockout cell line (A549) Human ZYG11A 1:3~1:4 Negative Online Inquiry

Background

ZYG11A Gene Knockout Cell Lines are genetically engineered cell lines in which the ZYG11A gene has been selectively deactivated, allowing researchers to investigate the role of this gene in various biological processes. The ZYG11A gene is involved in crucial cellular functions such as cell cycle regulation and the maintenance of genomic stability. By creating knockout cell lines, scientists can study the impact of ZYG11A loss on cellular behavior, including mechanisms associated with proliferation, differentiation, and apoptosis.

The primary mechanism of these knockout cell lines is the use of CRISPR/Cas9 technology, which facilitates precise gene editing to induce targeted gene inactivation. This allows for cumulative assessments of changes in cellular phenotypes, gene expression profiles, and signaling pathways that may be altered due to the absence of ZYG11A. Consequently, ZYG11A Gene Knockout Cell Lines serve as a valuable tool for elucidating the gene's functional contributions in both healthy and disease states, thereby advancing our understanding of potential therapeutic targets in cancer and other disorders.

In research settings, these cell lines are particularly integral for uncovering novel biological insights that may be difficult to achieve with traditional techniques. They are invaluable for drug discovery and the study of gene function in developmental biology and tumorigenesis, providing a unique platform for high-throughput screening of potential drug candidates. Compared to alternative methods, such as RNA interference, ZYG11A knockout cell lines offer permanent gene inactivation, ensuring that researchers can reliably assess phenotypic consequences without variability associated with transient knockdown approaches.

For researchers and clinicians alike, leveraging ZYG11A Gene Knockout Cell Lines enables a deeper exploration of gene function, aiding in the development of innovative therapeutics and diagnostic tools. Our company prides itself on being at the forefront of genetic research solutions, providing expertly validated tools that empower the scientific community to further their investigations in gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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