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ZW10 Knockout Cell Lines

Gene: ZW10

Official Full Name: zw10 kinetochore proteinprovided by HGNC

Gene Summary: This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33496 ZW10 Knockout cell line (HeLa) Human ZW10 1:3~1:6 Negative Online Inquiry
KO33497 ZW10 Knockout cell line (HCT 116) Human ZW10 1:2~1:4 Negative Online Inquiry
KO33498 ZW10 Knockout cell line (HEK293) Human ZW10 1:3~1:6 Negative Online Inquiry
KO33499 ZW10 Knockout cell line (A549) Human ZW10 1:3~1:4 Negative Online Inquiry

Background

ZW10 Gene Knockout Cell Lines are a specialized biological research tool designed to facilitate the study of gene function by creating cellular models lacking the ZW10 gene. ZW10 is an essential component of the mitotic checkpoint complex that governs the fidelity of chromosome segregation during cell division, and its inactivation has been linked to a variety of pathological conditions, including cancer. By utilizing these knockout cell lines, researchers can directly assess the consequences of ZW10 loss, allowing for in-depth analysis of related signaling pathways and cellular processes such as apoptosis, proliferation, and genomic stability.

The primary mechanism behind ZW10 knockout cells involves gene editing techniques, such as CRISPR/Cas9, which precisely disrupt the target gene, resulting in a model that allows for the observation of resultant phenotypic and molecular changes. This specificity makes them invaluable for investigating gene function within both basic and translational research settings. The implications of ZW10 knockout research are far-reaching, spanning from basic cellular biology to drug discovery and development, providing insights into mechanisms of disease and potential therapeutic interventions.

What sets ZW10 Gene Knockout Cell Lines apart from alternative models is their unparalleled specificity and reproducibility, enabling researchers to study ZW10's role in a controlled environment without the confounding effects other cellular components may introduce. Moreover, these cell lines can accelerate the development of targeted therapies by providing reliable data on cellular responses to treatment strategies aimed at restoring normal function.

By choosing ZW10 Gene Knockout Cell Lines, researchers and clinicians gain access to a state-of-the-art tool that offers a deeper understanding of gene function and its related pathways. This is particularly valuable for those pursuing innovative approaches to cancer treatment or looking to elucidate the complexities of mitotic regulation.

Our company prides itself on a robust commitment to advancing scientific knowledge through high-quality biological products coupled with expert support, ensuring that researchers are empowered in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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