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ZNHIT3 Knockout Cell Lines

Gene: ZNHIT3

Official Full Name: zinc finger HIT-type containing 3provided by HGNC

Gene Summary: Predicted to enable nuclear thyroid hormone receptor binding activity. Predicted to be involved in box C/D snoRNP assembly; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and snoRNA localization. Located in cytoplasm and nucleus. Implicated in PEHO syndrome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33324 ZNHIT3 Knockout cell line (HeLa) Human ZNHIT3 1:3~1:6 Negative Online Inquiry
KO33325 ZNHIT3 Knockout cell line (HCT 116) Human ZNHIT3 1:2~1:4 Negative Online Inquiry
KO33326 ZNHIT3 Knockout cell line (HEK293) Human ZNHIT3 1:3~1:6 Negative Online Inquiry
KO33327 ZNHIT3 Knockout cell line (A549) Human ZNHIT3 1:3~1:4 Negative Online Inquiry

Background

ZNHIT3 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed to facilitate the study of gene function by enabling the complete absence of the ZNHIT3 gene in a cellular context. This product utilizes advanced CRISPR/Cas9 genome-editing technology to create stable cell lines that lack ZNHIT3 expression, allowing researchers to observe the biological consequences of gene knockout in real-time.

The primary function of ZNHIT3 Gene Knockout Cell Lines is to elucidate the role of the ZNHIT3 gene in various cellular processes, including proliferation, differentiation, and response to stress. By observing the phenotypic and molecular changes that occur in these genetically modified cells, researchers can gain insights into the gene's involvement in pathophysiological conditions, such as cancer, metabolic disorders, and neurological diseases. The mechanisms of action involve dissecting the gene's interactions with other cellular components and signaling pathways, thus shedding light on its functional significance.

In a clinical research setting, these cell lines are pivotal for drug development, biomarker discovery, and therapeutic targeting. By providing a robust platform for functional analysis, ZNHIT3 Gene Knockout Cell Lines can aid in the identification of new therapeutic targets and improve the understanding of disease mechanisms at the cellular level.

What sets our ZNHIT3 Gene Knockout Cell Lines apart from alternative products is the rigor of our production process, which includes thorough validation of gene knockout efficiency and cell line stability. Additionally, our product is backed by comprehensive user support, including protocol optimization and troubleshooting guidance, ensuring that researchers can achieve reliable results.

For researchers and clinicians focused on advancing their understanding of genetic influences on health and disease, ZNHIT3 Gene Knockout Cell Lines provide an unparalleled resource that enhances experimental reproducibility and accelerates discovery. Our company is committed to excellence in synthetic biology and genetic engineering, offering a suite of top-tier biological products designed to empower scientific inquiry and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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