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ZNF860 Knockout Cell Lines

Gene: ZNF860

Official Full Name: zinc finger protein 860provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11925 ZNF860 Knockout cell line (HeLa) Human ZNF860 1:3~1:6 Negative Online Inquiry
KO11926 ZNF860 Knockout cell line (HCT 116) Human ZNF860 1:2~1:4 Negative Online Inquiry
KO11927 ZNF860 Knockout cell line (A549) Human ZNF860 1:3~1:4 Negative Online Inquiry

Background

ZNF860 Gene Knockout Cell Lines are a specialized biological tool designed for in-depth investigations into the functional roles of the ZNF860 gene, a zinc-finger transcription factor implicated in various cellular processes and disease mechanisms. These engineered cell lines possess a targeted deletion of the ZNF860 gene, enabling researchers to assess the gene's influence on cellular behavior, differentiation, and response to stimuli in a controlled environment.

The key function of the ZNF860 Gene Knockout Cell Lines lies in their ability to provide a knockout model essential for elucidating the gene's biological pathways. The mechanism involves the precise editing of the genome using advanced techniques such as CRISPR-Cas9, ensuring a definitive disruption of ZNF860 expression. This allows for comparative studies between knockout and wild-type cell lines to assess changes in gene expression, protein interactions, and metabolic responses, which are crucial for understanding the role of ZNF860 in cell biology.

The scientific importance of these cell lines is underscored by their applications across various research domains, including cancer biology, developmental biology, and neurobiology. By studying the consequences of ZNF860 knockout, researchers can generate insights into its potential roles in tumor suppression, cell cycle regulation, and cellular senescence, thereby identifying novel therapeutic targets.

Unlike traditional models, such as whole-organism knockouts or temporary knockdown systems, ZNF860 Gene Knockout Cell Lines offer a stable and reproducible platform with minimal off-target effects. This specificity allows for high-throughput screening and the potential for drug discovery applications targeting pathways modulated by ZNF860.

For researchers and clinicians aiming to advance their understanding of gene function and develop innovative therapies, these cell lines present a unique opportunity to delve into gene-related pathology with high precision. Our company boasts extensive expertise in the creation of genetically engineered models, ensuring that ZNF860 Gene Knockout Cell Lines are produced under rigorous quality control standards, thus equipping you with a reliable tool for pioneering your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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