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ZNF850 Knockout Cell Lines

Gene: ZNF850

Official Full Name: zinc finger protein 850provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11934 ZNF850 Knockout cell line (HCT 116) Human ZNF850 1:2~1:4 Negative Online Inquiry
KO11935 ZNF850 Knockout cell line (HEK293) Human ZNF850 1:3~1:6 Negative Online Inquiry
KO11936 ZNF850 Knockout cell line (A549) Human ZNF850 1:3~1:4 Negative Online Inquiry

Background

ZNF850 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to lack the expression of the ZNF850 gene. This product serves as an essential tool for researchers studying gene function, regulatory pathways, and the intricate roles of zinc-finger proteins in cellular processes. These knockout models provide a unique opportunity to elucidate the molecular mechanisms underlying various biological phenomena, including development, differentiation, and disease progression.

The ZNF850 gene is implicated in critical cellular functions and signals involved in the regulation of gene expression. By utilizing knockout cell lines, researchers can investigate the effects of ZNF850 deficiency on cell behavior, signaling pathways, and interactions with other genomic elements. The mechanisms of action typically include the modulation of transcriptional activity, leading to downstream effects on cell proliferation and apoptosis. This makes ZNF850 knockout cell lines a powerful system for assessing how disruptions to this specific gene influence overall cell function.

In terms of scientific importance, ZNF850 knockout cell lines have wide-ranging applications in both basic and translational research. They are particularly valuable for studying cancer biology, where understanding the contributions of specific genes to tumorigenesis and metastasis is crucial. Additionally, these cell lines can facilitate drug discovery efforts by providing a platform for screening potential therapeutics aimed at targeting specific pathways affected by the loss of ZNF850 function.

Distinct advantages of ZNF850 knockout cell lines include their specificity and reliability compared to other gene-editing strategies. Unlike transient RNA interference methods that may yield inconsistent results, these knockout lines provide stable and reproducible models that yield high-confidence data over extended periods. Furthermore, they allow for the assessment of gene function in a controlled environment, leading to clearer insights and implications for therapy development or basic biological understanding.

For researchers and clinicians, the ability to study the effects of targeted gene deletions accelerates discoveries that can ultimately translate into real-world applications, influencing everything from patient treatment modalities to the development of targeted therapies.

Our company excels in producing high-quality, rigorously validated biological products, including these ZNF850 Gene Knockout Cell Lines, making us a trusted collaborator in advancing scientific research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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