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ZNF829 Knockout Cell Lines

Gene: ZNF829

Official Full Name: zinc finger protein 829provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11950 ZNF829 Knockout cell line (HEK293) Human ZNF829 1:3~1:6 Negative Online Inquiry

Background

ZNF829 Gene Knockout Cell Lines are specifically engineered cell lines that have undergone precise genetic modifications to disrupt the expression of the ZNF829 gene, a transcription factor implicated in various cellular processes such as differentiation, proliferation, and apoptosis. These knockout cell lines provide invaluable tools for researchers seeking to elucidate the functional roles of ZNF829 in different biological contexts.

The key function of ZNF829 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function through loss-of-function assays. The knockout mechanism usually involves CRISPR-Cas9 technology, which enables targeted genomic edits, resulting in the complete ablation of ZNF829 expression. This allows scientists to explore the downstream effects of ZNF829 depletion on cellular signaling pathways, gene expression profiles, and phenotypic variations, contributing to a deeper understanding of developmental biology and disease mechanisms.

The scientific importance of ZNF829 Gene Knockout Cell Lines is underscored by their applications in both fundamental research and clinical settings. They serve as critical models for investigating cancer biology, neurodevelopmental disorders, and other pathological conditions where ZNF829 may play a pivotal role. Moreover, these cell lines can be instrumental in drug discovery, enabling researchers to screen for compounds that specifically target ZNF829-related pathways.

Compared to alternative models, ZNF829 Gene Knockout Cell Lines offer distinct advantages such as high specificity and reproducibility. Unlike conventional methods involving chemical inhibitors or RNA interference, the CRISPR-based gene knockout approach provides a permanent genetic alteration, ensuring that any observed effects are directly attributable to the loss of ZNF829 function.

For researchers, clinicians, and biotechnology professionals, the value of these knockout cell lines is clear: they provide a versatile platform for in-depth studies that can lead to significant advancements in our understanding of gene regulation and its implications in health and disease. Our company is committed to delivering high-quality biological products, underpinned by extensive scientific expertise, ensuring that our customers have access to state-of-the-art tools for their research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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