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ZNF804A Knockout Cell Lines

Gene: ZNF804A

Official Full Name: zinc finger protein 804Aprovided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger binding protein. Polymorphisms in this gene, especially rs1344706, are thought to confer increased susceptibility to schizophrenia, bipolar disorder, and heroin addiciton. [provided by RefSeq, Nov 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23390 ZNF804A Knockout cell line (HCT 116) Human ZNF804A 1:2~1:4 Negative Online Inquiry

Background

ZNF804A Gene Knockout Cell Lines represent a cutting-edge biological product designed for advanced genetic research and therapeutic exploration. These cell lines are genetically engineered to achieve complete knockout of the ZNF804A gene, a critical gene implicated in various neurological disorders, including schizophrenia and bipolar disorder. By precisely altering the genome, these cell lines enable researchers to study the contribution of ZNF804A to disease phenotypes, cellular processes, and molecular mechanisms.

The primary function of the ZNF804A knockout is to facilitate the investigation of gene function through the observation of phenotypic changes in the absence of this specific gene. Utilizing CRISPR-Cas9 technology, these cell lines offer a reliable method for gene editing, allowing researchers to elucidate the role of ZNF804A in neurodevelopment, synaptic plasticity, and neurodegeneration. This understanding can lead to the identification of novel targets for drug development and therapeutic interventions.

Scientifically, ZNF804A Gene Knockout Cell Lines hold significant importance in both research and clinical settings. They provide a model for simulating genetic variations found in patients, enabling studies on gene-environment interactions and the mechanisms driving neuropsychiatric diseases. Furthermore, these cell lines support high-throughput screening of potential pharmacological agents that may restore normal function in cells lacking ZNF804A.

What sets our ZNF804A knockout cell lines apart from conventional alternatives is the precision of the genetic edit, the robustness of cell viability, and the ease of use in experimental protocols. Researchers can confidently rely on these highly characterized cell lines for reproducible results, saving time and resources often lost in less optimized models.

For researchers and clinicians alike, these knockout cell lines offer transformative potential in advancing both basic science and clinical applications. The insights gained from these models may lead to better diagnostic tools and therapeutic strategies, ultimately improving patient outcomes in neuropsychiatric conditions.

At our company, we specialize in the development and provision of high-quality biological products, backed by years of expertise in genetic engineering. Our commitment to supporting scientific discovery ensures you receive not just a product but a gateway to innovation in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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