Gene: ZNF783
Official Full Name: zinc finger protein 783provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11980 | ZNF783 Knockout cell line (HeLa) | Human | ZNF783 | 1:3~1:6 | Negative | Online Inquiry |
KO11981 | ZNF783 Knockout cell line (HCT 116) | Human | ZNF783 | 1:2~1:4 | Negative | Online Inquiry |
KO11982 | ZNF783 Knockout cell line (HEK293) | Human | ZNF783 | 1:3~1:6 | Negative | Online Inquiry |
KO11983 | ZNF783 Knockout cell line (A549) | Human | ZNF783 | 1:3~1:4 | Negative | Online Inquiry |
ZNF783 Gene Knockout Cell Lines are specifically engineered cellular models wherein the ZNF783 gene has been rendered non-functional through precise gene-editing techniques such as CRISPR/Cas9. The ZNF783 gene encodes a zinc-finger protein that plays a crucial role in various cellular processes, including transcriptional regulation and cellular differentiation. By creating knockout cell lines, researchers can explore the downstream effects of ZNF783 loss, elucidate its functional significance, and investigate its role in diseases, particularly in the context of cancer and other pathologies where gene dysregulation is implicated.
The primary function of ZNF783 Gene Knockout Cell Lines enables the study of gene function through comparison with wild-type controls. The absence of ZNF783 allows for an exploration of compensatory mechanisms and identifies pathways that are activated or altered due to its loss. This is particularly valuable in drug discovery and development efforts, where understanding the gene's role can influence therapeutic strategies.
In scientific research and clinical settings, these knockout cell lines offer a robust platform for high-throughput screening, functional assays, and molecular characterization, significantly contributing to the knowledge base surrounding gene-gene interactions and disease mechanisms. Their use can expand the understanding of tumor biology and lead to the identification of potential diagnostic or therapeutic targets.
The advantages of utilizing ZNF783 Gene Knockout Cell Lines include enhanced specificity and reliability over traditional pharmacological inhibition methods. Unlike small molecules that may have off-target effects, these knockout cell lines provide a clean genetic model for direct observation of ZNF783-related phenotypes. Researchers benefit from the availability of well-characterized, reproducible cell lines that accelerate experimental timelines and improve data quality.
The value of ZNF783 Gene Knockout Cell Lines to researchers and clinicians is profound, as they facilitate exploring gene function in a controlled environment, fostering scientific discovery that can translate to real-world applications in medicine. With our company’s expertise in genetic engineering and commitment to providing high-quality biological products, we offer a reliable resource for advancing research in gene function and therapeutics.
Please note that all services are for research use only. Not intended for any clinical use.
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