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ZNF777 Knockout Cell Lines

Gene: ZNF777

Official Full Name: zinc finger protein 777provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity. Involved in negative regulation of DNA-templated transcription; negative regulation of cell population proliferation; and protein heterooligomerization. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27765 ZNF777 Knockout cell line (HeLa) Human ZNF777 1:3~1:6 Negative Online Inquiry
KO27766 ZNF777 Knockout cell line (HCT 116) Human ZNF777 1:2~1:4 Negative Online Inquiry
KO27767 ZNF777 Knockout cell line (HEK293) Human ZNF777 1:3~1:6 Negative Online Inquiry
KO27768 ZNF777 Knockout cell line (A549) Human ZNF777 1:3~1:4 Negative Online Inquiry

Background

ZNF777 Gene Knockout Cell Lines are a cutting-edge biological tool specifically engineered to investigate the functional roles of the ZNF777 gene, which has been implicated in various cellular processes, including gene regulation and oncogenesis. These cell lines are created using CRISPR/Cas9 technology, allowing for precise and targeted modifications within the genome, effectively silencing the expression of the ZNF777 gene. This knockout approach enables researchers to explore the physiological and pathological consequences of ZNF777 loss in a controlled environment.

The primary mechanism of action involves the introduction of specific guide RNAs that direct the Cas9 nuclease to the ZNF777 gene locus, resulting in double-strand breaks and subsequent gene disruption. This clear loss-of-function model provides insights into the gene's involvement in cancer pathways, cell cycle regulation, and other biological processes, making it a valuable resource for both basic research and translational applications.

The scientific importance of ZNF777 Gene Knockout Cell Lines is profound; they serve as a pivotal model for understanding diseases tied to aberrant gene expression and regulation. Researchers can utilize these cell lines to elucidate the mechanisms of drug action, discover biomarkers for disease, and identify potential therapeutic targets. Furthermore, the ability to assess the impact of ZNF777 knockout on cell behavior paves the way for enhanced therapeutic strategies in oncology and regenerative medicine.

One of the specific advantages of our ZNF777 Gene Knockout Cell Lines is the high efficiency and specificity of the knockout, minimizing off-target effects commonly associated with traditional gene-editing methods. In addition, our lines undergo rigorous validation and quality control, ensuring reliability and reproducibility in experimental outcomes. This level of assurance is crucial for researchers aiming to produce publishable findings.

For researchers and clinicians dedicated to uncovering the complexities of gene function, ZNF777 Gene Knockout Cell Lines represent not only a vital resource but also an opportunity to drive innovation in life sciences. Our company prides itself on being at the forefront of genetic engineering technologies, providing high-quality products that empower scientific discovery and clinical advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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