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ZNF70 Knockout Cell Lines

Gene: ZNF70

Official Full Name: zinc finger protein 70provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytoplasm and megasporocyte nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34675 ZNF70 Knockout cell line (HeLa) Human ZNF70 1:3~1:6 Negative Online Inquiry
KO34676 ZNF70 Knockout cell line (HCT 116) Human ZNF70 1:2~1:4 Negative Online Inquiry
KO34677 ZNF70 Knockout cell line (HEK293) Human ZNF70 1:3~1:6 Negative Online Inquiry
KO34678 ZNF70 Knockout cell line (A549) Human ZNF70 1:3~1:4 Negative Online Inquiry

Background

ZNF70 Gene Knockout Cell Lines are specialized cellular models that have undergone targeted genomic alterations to disrupt the expression of the ZNF70 gene, a member of the zinc finger protein family associated with various regulatory functions in cellular processes, including transcription and signal transduction. These knockout cell lines serve as a powerful tool for researchers exploring the role of ZNF70 in biological systems and disease states.

The key function of ZNF70 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function and interaction through the absence of the ZNF70 protein. By utilizing CRISPR/Cas9 or similar gene-editing techniques, these cell lines allow for the investigation of phenotypic changes, signaling pathways, and gene expression profiles that result from the loss of ZNF70. This enables researchers to elucidate the contributions of ZNF70 in cellular growth, differentiation, and response to external stimuli.

Scientifically, the ZNF70 knockout model has significant implications in both basic and translational research. In cancer studies, for instance, understanding the role of ZNF70 in tumorigenesis and metastasis may lead to novel therapeutic targets. Furthermore, these cell lines are invaluable for drug discovery and development, enabling the identification of compounds that may selectively affect ZNF70-related pathways.

Compared to conventional methods of gene manipulation, ZNF70 Gene Knockout Cell Lines provide a streamlined and efficient approach to gene function analysis without the off-target effects often associated with traditional knockdown methods. They represent a more stable solution than transient transfection, ensuring consistent results across experiments and making them particularly beneficial for replicative studies.

For researchers and clinicians seeking to unravel the complexities of gene regulation and its repercussions in health and disease, ZNF70 Gene Knockout Cell Lines offer unmatched precision and reliability. Our company specializes in developing high-quality biological models and offers extensive support, enabling users to leverage our products to advance their research effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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