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ZNF692 Knockout Cell Lines

Gene: ZNF692

Official Full Name: zinc finger protein 692provided by HGNC

Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of gluconeogenesis. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12061 ZNF692 Knockout cell line (HeLa) Human ZNF692 1:3~1:6 Negative Online Inquiry
KO12062 ZNF692 Knockout cell line (HCT 116) Human ZNF692 1:2~1:4 Negative Online Inquiry
KO12063 ZNF692 Knockout cell line (HEK293) Human ZNF692 1:3~1:6 Negative Online Inquiry
KO12064 ZNF692 Knockout cell line (A549) Human ZNF692 1:3~1:4 Negative Online Inquiry

Background

ZNF692 gene knockout cell lines are specialized cellular models in which the ZNF692 gene has been systematically disrupted or deleted, allowing researchers to investigate its biological functions and pathogenic roles. These cell lines serve as invaluable tools to explore gene function, elucidate signaling pathways, and assess the gene's impact on various cellular processes such as differentiation, proliferation, and apoptosis. The knockout of ZNF692 enables scientists to observe phenotypic changes and molecular alterations that arise from the absence of this particular transcription factor, which is known to be involved in diverse cellular mechanisms.

The primary mechanism at play is the loss of function associated with the ZNF692 gene, allowing for the exploration of downstream effects on gene expression and cellular behavior. Researchers can utilize techniques such as RNA sequencing and quantitative PCR to measure how the absence of ZNF692 impacts gene regulation and cellular activity. This functional analysis is essential for understanding the gene’s role in normal physiology and its potential contributions to diseases, particularly in oncology and developmental biology.

From a scientific standpoint, ZNF692 knockout cell lines offer critical insights into complex biological systems and disease mechanisms, facilitating drug discovery and therapeutic development. Their application in high-throughput screening methods enhances the ability to identify novel drug targets associated with ZNF692-related pathways.

Compared to conventional research tools, such as wild-type cell lines or transient knockdown approaches, ZNF692 knockout cell lines provide a stable and permanent solution for gene deletion studies. This stability allows for reproducible results over extended experimental periods and facilitates long-term studies in a range of experimental conditions.

Moreover, the value of ZNF692 knockout cell lines extends to their versatility; they can be used to simulate disease states, assess drug responses, and contribute to the development of gene therapies. For researchers and clinicians alike, these knockout models bridge the gap between fundamental research and its clinical applications, making them a pivotal addition to your experimental repertoire.

Our company prides itself on delivering high-quality genetic models backed by extensive expertise in gene editing technologies. We are committed to advancing scientific research and therapeutic discovery through innovative biological products tailored to meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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