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ZNF680 Knockout Cell Lines

Gene: ZNF680

Official Full Name: zinc finger protein 680provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12065 ZNF680 Knockout cell line (HeLa) Human ZNF680 1:3~1:6 Negative Online Inquiry
KO12066 ZNF680 Knockout cell line (HCT 116) Human ZNF680 1:2~1:4 Negative Online Inquiry
KO12067 ZNF680 Knockout cell line (HEK293) Human ZNF680 1:3~1:6 Negative Online Inquiry
KO12068 ZNF680 Knockout cell line (A549) Human ZNF680 1:3~1:4 Negative Online Inquiry

Background

ZNF680 Gene Knockout Cell Lines are genetically modified cell lines designed to specifically lack the ZNF680 gene, which encodes a protein involved in various cellular processes, including transcriptional regulation and chromatin remodeling. These knockout cell lines function as powerful tools for researchers investigating the role of ZNF680 in cellular dynamics, gene expression, and its associated biological pathways. By eliminating the expression of this gene, researchers can observe phenotypic changes and elucidate its contribution to cellular function, disease mechanisms, and potential therapeutic targets.

The key mechanism behind these cell lines involves the use of CRISPR-Cas9 technology, which allows for precise editing of the genome. The Cas9 protein, guided by RNA sequences complementary to the ZNF680 gene, creates double-strand breaks in the DNA, leading to frame shifts or deletions that effectively silence the gene. This targeted approach not only facilitates the study of gene function but also aids in understanding gene interactions, pathways involved in development, and responses to pharmacological agents.

The scientific importance of ZNF680 knockout cell lines lies in their diverse applications in biomedical research and clinical settings. They serve as invaluable models for studying the implications of ZNF680 in diseases such as cancer, neurodegeneration, and metabolic disorders. Furthermore, these cell lines can enhance our understanding of genetic contributions to drug responses, helping in the development of personalized medicine strategies.

One of the primary advantages of ZNF680 gene knockout cell lines compared to traditional models is their specificity and efficiency in gene editing, providing more accurate results and reducing variability in experiments. Moreover, along with user-friendly protocols, these cell lines are compatible with high-throughput screening, enabling extensive studies that save time and resources.

For researchers and clinicians alike, the ZNF680 knockout cell lines represent a significant leap forward in the ability to dissect the molecular basis of various diseases and to explore innovative therapeutic avenues. Our company offers expertly crafted biological products that meet stringent quality standards, ensuring reliability and reproducibility in scientific research. With our commitment to innovation and customer support, we empower researchers to unlock new discoveries in the field of genetics and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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