Gene: ZNF658
Official Full Name: zinc finger protein 658provided by HGNC
Gene Summary: Enables transcription cis-regulatory region binding activity. Involved in cellular response to zinc ion; negative regulation of DNA-templated transcription; and ribosome biogenesis. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28253 | ZNF658 Knockout cell line (HeLa) | Human | ZNF658 | 1:3~1:6 | Negative | Online Inquiry |
KO28254 | ZNF658 Knockout cell line (HCT 116) | Human | ZNF658 | 1:2~1:4 | Negative | Online Inquiry |
KO28255 | ZNF658 Knockout cell line (HEK293) | Human | ZNF658 | 1:3~1:6 | Negative | Online Inquiry |
KO28256 | ZNF658 Knockout cell line (A549) | Human | ZNF658 | 1:3~1:4 | Negative | Online Inquiry |
ZNF658 Gene Knockout Cell Lines are an innovative biological tool created to study the specific functions of the ZNF658 gene, a critical player in various cellular processes, including transcriptional regulation and cellular differentiation. Gene knockout technology involves the targeted inactivation of a specific gene, enabling researchers to investigate its role in biological systems by observing the resultant phenotypic changes in the cell lines.
The ZNF658 gene is implicated in several pathways linked to developmental biology and disease states, particularly in cancer. Through gene editing techniques, such as CRISPR/Cas9, the ZNF658 gene is disrupted, enabling researchers to delve into its mechanistic roles. The resulting knockout cell lines provide an effective platform for examining changes in gene expression, molecular signaling pathways, and cellular behaviors, facilitating deeper insights into ZNF658’s function and contributions to pathologies.
The scientific importance of these cell lines extends to both research and clinical settings. Researchers can utilize ZNF658 knockout lines to explore potential therapeutic strategies or drug targets, making it a valuable asset in the fields of molecular biology and pharmacology. Additionally, these cell lines are crucial for toxicology assessments and biomarker validation, providing a robust framework for translational studies aimed at improving disease diagnosis and treatment.
Compared to alternative models, ZNF658 Gene Knockout Cell Lines offer distinct advantages, including precise genetic alterations and the ability to evaluate real-time cellular responses in a controlled environment. These knockout lines are specifically tailored for versatility, allowing for the assessment of numerous biological variables while maintaining the integrity of the host cellular context.
For researchers and clinicians seeking to advance their understanding of gene function and disease mechanisms, the ZNF658 Gene Knockout Cell Lines present a pivotal resource. The meticulous design and verification of these lines ensure high-quality results, ultimately empowering the scientific community to enhance their research outcomes. As a leader in biotechnological innovation, our company is committed to delivering cutting-edge biological products that meet the evolving needs of researchers and clinicians alike.
Please note that all services are for research use only. Not intended for any clinical use.
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