Gene: ZNF638
Official Full Name: zinc finger protein 638provided by HGNC
Gene Summary: The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27638 | ZNF638 Knockout cell line (HeLa) | Human | ZNF638 | 1:3~1:6 | Negative | Online Inquiry |
KO27639 | ZNF638 Knockout cell line (HCT 116) | Human | ZNF638 | 1:2~1:4 | Negative | Online Inquiry |
KO27640 | ZNF638 Knockout cell line (HEK293) | Human | ZNF638 | 1:3~1:6 | Negative | Online Inquiry |
KO27641 | ZNF638 Knockout cell line (A549) | Human | ZNF638 | 1:3~1:4 | Negative | Online Inquiry |
ZNF638 Gene Knockout Cell Lines are genetically engineered cell lines that have had the ZNF638 gene specifically inactivated using CRISPR-Cas9 technology. This product is designed to facilitate the study of gene function, particularly in the context of cellular processes such as differentiation, proliferation, and apoptosis. ZNF638 encodes a zinc finger protein implicated in various regulatory functions, including transcriptional control and potentially in oncogenesis, thus its knockout offers insights into its role in both normal physiology and disease states.
The primary mechanism of action of ZNF638 knockout cell lines revolves around the targeted disruption of the ZNF638 gene, eliminating its expression and allowing researchers to assess the phenotypic consequences in a controlled environment. Through the observation of cellular behavior following gene knockout, scientists can elucidate the downstream effects of ZNF638 loss, providing valuable information for understanding disease mechanisms, especially in cancer research where ZNF638 may play a role in tumorigenesis.
The significance of ZNF638 knockout cell lines extends to various applications in research and clinical settings, including drug discovery, genetic pathway mapping, and the development of novel therapeutic strategies. These cell lines allow researchers to investigate potential therapeutic targets and the molecular mechanisms of diseases, providing a platform for translational research.
What sets our ZNF638 knockout cell lines apart from alternatives is our commitment to high-quality production and validation. Each line is rigorously tested for the absence of ZNF638 expression and characterized for stability and reproducibility in lab settings. This ensures that researchers can rely on the integrity of their experimental systems, thus enhancing the quality of their scientific findings.
In an environment where the need for precise models is critical for advancing biomedical research, ZNF638 Gene Knockout Cell Lines represent an invaluable tool for both established and emerging scientists. By choosing our lines, users benefit from our company’s deep expertise in genetic engineering and our commitment to supporting researchers in their journey toward discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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