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ZNF599 Knockout Cell Lines

Gene: ZNF599

Official Full Name: zinc finger protein 599provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23525 ZNF599 Knockout cell line (HeLa) Human ZNF599 1:3~1:6 Negative Online Inquiry
KO23526 ZNF599 Knockout cell line (HEK293) Human ZNF599 1:3~1:6 Negative Online Inquiry
KO23527 ZNF599 Knockout cell line (A549) Human ZNF599 1:3~1:4 Negative Online Inquiry

Background

ZNF599 Gene Knockout Cell Lines are sophisticated biological tools engineered to specifically disrupt the ZNF599 gene within various cellular models. ZNF599, a member of the zinc finger protein family, plays crucial roles in gene regulation, cellular signaling, and development. By utilizing CRISPR-Cas9 technology, these knockout cell lines facilitate precise gene editing, allowing researchers to study the effects of ZNF599 loss-of-function in a controlled environment.

The primary mechanism involves the introduction of specific guide RNAs (gRNAs) targeting ZNF599, which leads to the formation of double-strand breaks in the genomic DNA. This response activates the cell's inherent DNA repair pathways, often resulting in insertions or deletions (indels) that effectively inactivate the gene. This process enables scientists to explore the phenotypic consequences of ZNF599 knockout, thus enhancing our understanding of its biological roles in various contexts, including cancer research, developmental biology, and gene therapy.

In research and clinical settings, ZNF599 Gene Knockout Cell Lines serve as invaluable tools for dissecting the molecular mechanisms underlying diseases where ZNF599 dysregulation is implicated. These cell lines facilitate the validation of therapeutic targets and the development of novel intervention strategies.

A unique advantage of our ZNF599 Gene Knockout Cell Lines is their high specificity and efficiency, significantly reducing off-target effects commonly associated with earlier gene-editing techniques. This precision enhances the reliability of experimental outcomes, making them an ideal choice for researchers seeking robust and reproducible data.

Moreover, our rigorous quality control procedures ensure that each cell line is thoroughly validated, providing peace of mind for researchers. The accessibility of these cell lines enables both academic and industrial labs to accelerate their research, ultimately driving discoveries that have the potential to translate into clinically relevant therapies.

With years of expertise in developing high-quality biological products, our company is dedicated to supporting the scientific community by providing reliable, cutting-edge solutions that empower researchers and clinicians in their quest to advance human health.

Please note that all services are for research use only. Not intended for any clinical use.

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