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ZNF584 Knockout Cell Lines

Gene: ZNF584

Official Full Name: zinc finger protein 584provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37316 ZNF584 Knockout cell line (HeLa) Human ZNF584 1:3~1:6 Negative Online Inquiry
KO37317 ZNF584 Knockout cell line (HCT 116) Human ZNF584 1:2~1:4 Negative Online Inquiry
KO37318 ZNF584 Knockout cell line (HEK293) Human ZNF584 1:3~1:6 Negative Online Inquiry
KO37319 ZNF584 Knockout cell line (A549) Human ZNF584 1:3~1:4 Negative Online Inquiry

Background

ZNF584 Gene Knockout Cell Lines are specialized cellular models engineered to selectively inactivate the ZNF584 gene, providing invaluable tools for the study of gene function, regulation, and associated biological pathways. By utilizing CRISPR/Cas9 technology, these cell lines facilitate precise genomic editing, allowing researchers to create a uniform, reproducible environment for investigating the role of ZNF584 in various physiological and pathophysiological contexts.

The primary function of ZNF584 Gene Knockout Cell Lines lies in their ability to elucidate the biological impact of ZNF584 loss-of-function. This is particularly crucial in understanding the implications of ZNF584 gene alterations in diseases such as cancer or neurological disorders. Upon knockout, researchers can assess cellular changes, differentiation patterns, and metabolic shifts that arise from the absence of the ZNF584 protein, thereby providing insights into its function in transcriptional regulation and chromatin organization.

The scientific importance of these knockout cell lines is underscored by their broad applications in both basic and translational research. In a clinical setting, they can aid in discovering potential therapeutic targets and biomarkers, contributing to enhanced stratification of disease subtypes. Their utility extends to drug discovery, where understanding the functional consequences of ZNF584 knockout could inform treatment strategies and therapeutic development.

Compared to other genetic tools, ZNF584 Gene Knockout Cell Lines offer distinct advantages; they provide a complete knockout model rather than just knockdown, enabling more comprehensive studies of gene function without the confounding effects of residual protein activity. This complete inactivation is crucial for researchers needing clear and definitive conclusions about gene roles in complex biological systems.

For researchers and clinicians striving to push the boundaries of genetic research and apply findings to real-world applications, ZNF584 Gene Knockout Cell Lines present a valuable resource. Their development represents our company's commitment to providing cutting-edge biological tools that empower scientific discovery. With expertise in genomic technologies and a deep understanding of cellular biology, we offer high-quality products that meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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