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ZNF583 Knockout Cell Lines

Gene: ZNF583

Official Full Name: zinc finger protein 583provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23553 ZNF583 Knockout cell line (HEK293) Human ZNF583 1:3~1:6 Negative Online Inquiry
KO23554 ZNF583 Knockout cell line (A549) Human ZNF583 1:3~1:4 Negative Online Inquiry

Background

ZNF583 Gene Knockout Cell Lines are advanced genetic tools that facilitate the study of the zinc finger protein 583 (ZNF583), a transcription factor known to play significant roles in gene regulation and various cellular processes. These cell lines have been engineered using CRISPR-Cas9 technology to create a precise deletion of the ZNF583 gene, allowing researchers to investigate its functional effects in a controlled environment.

The key function of ZNF583 Gene Knockout Cell Lines lies in their ability to elucidate the role of ZNF583 in specific biological pathways. By silencing ZNF583, researchers can observe phenotypic changes and alterations in gene expression profiles, providing insights into the gene's involvement in cellular functions such as proliferation, differentiation, and apoptosis. This tool enhances our understanding of the underlying mechanisms of diseases, including cancer, where aberrant regulation of transcription factors may have deleterious effects.

From a scientific perspective, ZNF583 knockout cell lines are invaluable for both basic and applied research. They serve as models for exploring the gene's contribution to malignancies and other pathological states, and they can also be employed in drug testing and development, ultimately aiding the discovery of new therapeutic strategies.

One of the notable advantages of the ZNF583 Gene Knockout Cell Lines is their specificity and efficiency. Compared to traditional knockout technologies, the CRISPR-Cas9 method offers a faster and more reliable approach to gene editing, thereby minimizing off-target effects. This precision is crucial for researchers aiming to generate reproducible and robust experimental data.

For researchers and clinicians striving to advance their understanding of gene function and its implications in disease, ZNF583 Gene Knockout Cell Lines offer a powerful resource. With detailed characterization and robust performance, these cell lines can significantly enhance the quality and scale of research studies.

Our company prides itself on providing high-quality biological products backed by extensive expertise in genetic engineering and cellular biology. Our commitment to scientific excellence ensures that ZNF583 Gene Knockout Cell Lines are rigorously validated, ultimately supporting the research community in their quest for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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