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ZNF582 Knockout Cell Lines

Gene: ZNF582

Official Full Name: zinc finger protein 582provided by HGNC

Gene Summary: The protein encoded by this gene is a zing finger protein and putative transcription factor that is highly methylated in cervical cancers. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23555 ZNF582 Knockout cell line (HEK293) Human ZNF582 1:3~1:6 Negative Online Inquiry
KO23556 ZNF582 Knockout cell line (A549) Human ZNF582 1:3~1:4 Negative Online Inquiry

Background

ZNF582 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the targeted inactivation of the ZNF582 gene, which is associated with critical regulatory functions in gene expression and cellular processes. Utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with robust systems to study the functional role of ZNF582 in various biological contexts, such as development, differentiation, and disease pathology.

The primary mechanism by which ZNF582 gene knockout works involves the introduction of a double-strand break at the ZNF582 locus, prompting the cell's repair machinery to create an edit that disrupts gene function. This knockout strategy allows for the analysis of phenotypic changes and offers insights into the gene's involvement in cellular mechanisms and potential associations with disorders, particularly in cancer and neurodegeneration.

The scientific importance of ZNF582 Gene Knockout Cell Lines is underscored by their application in drug discovery, biomarker identification, and functional genomics studies. In clinical settings, these models can accelerate the understanding of gene-disease relationships and assist in the development of targeted therapies tailored to patient-specific genetic profiles.

Compared to alternatives, such as conventional siRNA-based approaches or other gene-editing tools, ZNF582 Gene Knockout Cell Lines offer enhanced specificity, durability, and ease of use, which significantly improves experimental reproducibility. The permanent gene inactivation provides a stable platform for long-term studies, allowing for comprehensive analyses of cellular behavior over extended periods.

For researchers and clinicians invested in gene function and therapeutic development, these cell lines represent an invaluable resource that combines precision editing with versatile applications. Our company brings years of expertise in genetic engineering and cell culture solutions, ensuring that our ZNF582 Gene Knockout Cell Lines are of the highest quality to meet the evolving demands of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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