Gene: ZNF578
Official Full Name: zinc finger protein 578provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23672 | ZNF578 Knockout cell line (HEK293) | Human | ZNF578 | 1:3~1:6 | Negative | Online Inquiry |
ZNF578 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the ZNF578 gene's role in various biological processes and disease mechanisms. These cell lines are generated using advanced gene editing techniques, such as CRISPR-Cas9, to create precise disruptions in the ZNF578 gene, effectively leading to complete gene knockout. This targeted approach allows researchers to investigate the functional implications of ZNF578 loss, including its effects on cellular proliferation, differentiation, and response to stimuli.
The key function of ZNF578 Gene Knockout Cell Lines lies in their capability to provide insights into gene function and regulatory networks. By analyzing the phenotypic and molecular changes in these cell lines, scientists can elucidate the pathways influenced by ZNF578, contributing to a broader understanding of its involvement in various diseases, including cancer and neurodegeneration. Furthermore, the knockout lines serve as invaluable tools for drug screening and the development of targeted therapies, enabling researchers to assess the efficacy of potential compounds in a controlled genetic context.
The scientific importance of these cell lines extends to both research and clinical settings. With their ability to model gene function accurately, they enhance the potential for discovering novel therapeutic targets and biomarkers. Compared to traditional cell lines, ZNF578 Gene Knockout Cell Lines offer specific and reproducible phenotypic outcomes, thus ensuring more reliable data for hypothesis testing.
A unique advantage of our ZNF578 Gene Knockout Cell Lines is their ease of use and customization options, allowing researchers to tailor the systems for their specific experimental needs. This mitigates the limitations often encountered with non-targeted approaches, providing a clear pathway to understanding the biological implications of gene disruption.
In conclusion, ZNF578 Gene Knockout Cell Lines represent a powerful resource for both academic and pharmaceutical research, unlocking the potential for transformative discoveries in the field of genetics and molecular biology. Our company, with its commitment to high-quality, advanced biological tools and expertise in genetic engineering, offers these innovative cell lines to empower scientists in their quest for understanding the fundamental roles of genes in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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