Gene: ZNF577
Official Full Name: zinc finger protein 577provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24649 | ZNF577 Knockout cell line (HCT 116) | Human | ZNF577 | 1:2~1:4 | Negative | Online Inquiry |
KO24650 | ZNF577 Knockout cell line (HEK293) | Human | ZNF577 | 1:3~1:6 | Negative | Online Inquiry |
ZNF577 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF577 gene, known for its role in regulating transcription and impacting various biological processes, has been specifically disrupted. By employing advanced CRISPR/Cas9 technology, these cell lines enable precise alterations in the genome, providing researchers with an invaluable tool to investigate the gene’s functionality, implications in disease states, and its role in cellular pathways.
The primary mechanism behind the ZNF577 Gene Knockout Cell Lines is the induced error in DNA repair following Cas9-mediated double-strand break creation, leading to the loss of function of the ZNF577 gene. This knockout allows for the observation of phenotypic changes, facilitating the study of gene interactions, signaling mechanisms, and the resultant effects on cellular behavior. Researchers can utilize these cell lines to further delve into cancer biology, neurobiology, and developmental processes, ultimately contributing to a deeper understanding of various pathologies and potential therapeutic strategies.
The scientific importance of these cell lines lies in their application across multiple research fields, particularly in elucidating the biological functions influenced by ZNF577 and its interactions with other genes. In clinical settings, such applications can lead to the identification of novel drug targets or biomarkers, enhancing personalized medicine approaches.
Compared to conventional methods of gene alteration, ZNF577 Gene Knockout Cell Lines offer unparalleled specificity and efficiency, greatly reducing off-target effects and allowing for higher fidelity in experimental outcomes. Their robust design and reliability make them superior tools for investigators aiming to elucidate complex biological questions.
For researchers and clinicians eager to expand their understanding of gene functionality and bioinformation, ZNF577 Gene Knockout Cell Lines represent a critical asset. Our company brings years of expertise in genetic engineering and cell line development, ensuring that you receive high-quality, reproducible products tailored for your scientific needs. We are dedicated to advancing biological research by providing innovative tools that empower discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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