Gene: ZNF490
Official Full Name: zinc finger protein 490provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12198 | ZNF490 Knockout cell line (HeLa) | Human | ZNF490 | 1:3~1:6 | Negative | Online Inquiry |
KO12199 | ZNF490 Knockout cell line (HCT 116) | Human | ZNF490 | 1:2~1:4 | Negative | Online Inquiry |
KO12200 | ZNF490 Knockout cell line (HEK293) | Human | ZNF490 | 1:3~1:6 | Negative | Online Inquiry |
KO12201 | ZNF490 Knockout cell line (A549) | Human | ZNF490 | 1:3~1:4 | Negative | Online Inquiry |
ZNF490 Gene Knockout Cell Lines are a cutting-edge tool in genetic research, specifically designed to facilitate the study of the ZNF490 gene, which is implicated in various cellular processes and disease states. These cell lines are created using advanced CRISPR/Cas9 technology to induce precise deletions of the ZNF490 gene, effectively creating a knockout model that allows researchers to explore the functional consequences of loss-of-function mutations.
The primary function of ZNF490 knockout cell lines involves the elucidation of gene function in relation to cell growth, differentiation, and response to external stimuli. By completely knocking out ZNF490, researchers can dissect the molecular pathways it influences, providing insights into its role in diseases such as cancer, neurodegeneration, and metabolic disorders. The simplicity and efficiency of the CRISPR/Cas9 method ensure a high rate of successful gene editing, while the stability of these knockout lines enables reproducible experimental results.
Scientifically, ZNF490 knockout cell lines hold immense value in both basic and translational research settings. They serve as pivotal models for studying gene function and interaction networks, drug discovery, and the development of targeted therapies. Moreover, these cell lines facilitate high-throughput screening processes, allowing researchers to identify novel compounds that may modulate the function of genes associated with disease.
What sets ZNF490 knockout cell lines apart from traditional genetic models is their unparalleled specificity and versatility. Unlike older methods, which often yield variable results and require extensive validation, our cell lines are rigorously tested for consistent gene disruptions and robust performance across different experimental setups. This reliability accelerates research timelines and enhances the confidence in experimental outcomes for researchers and clinicians alike.
Given the increasing demand for precise and functional models in the era of personalized medicine, ZNF490 knockout cell lines represent an invaluable asset for laboratories focused on cutting-edge genetic studies. Our company prides itself on expertise in genetic engineering and cell line development, ensuring that our products meet the highest scientific standards and are backed by robust technical support to assist users in their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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