Gene: ZNF485
Official Full Name: zinc finger protein 485provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27579 | ZNF485 Knockout cell line (HeLa) | Human | ZNF485 | 1:3~1:6 | Negative | Online Inquiry |
KO27580 | ZNF485 Knockout cell line (HCT 116) | Human | ZNF485 | 1:2~1:4 | Negative | Online Inquiry |
KO27581 | ZNF485 Knockout cell line (HEK293) | Human | ZNF485 | 1:3~1:6 | Negative | Online Inquiry |
KO27582 | ZNF485 Knockout cell line (A549) | Human | ZNF485 | 1:3~1:4 | Negative | Online Inquiry |
ZNF485 Gene Knockout Cell Lines represent a sophisticated tool for investigating gene function and the underlying mechanisms of genetic regulation. These engineered cell lines have been developed through targeted gene editing technologies, specifically CRISPR-Cas9, to introduce precise deletions within the ZNF485 locus. As a zinc finger protein, ZNF485 plays a crucial role in various biological processes, including transcriptional regulation and cell differentiation; thus, these knockout cell lines are instrumental in elucidating its function.
The primary function of ZNF485 Gene Knockout Cell Lines lies in their ability to provide an experimental platform that allows researchers to study the phenotypic consequences of ZNF485 loss-of-function. By observing changes in cellular behaviors, signaling pathways, and gene expression profiles associated with the knockout, scientists can gain invaluable insights into the role of ZNF485 in development and disease, particularly in cancers and other disorders linked to dysregulation of gene expression.
In clinical and research settings, these knockout cell lines are essential for the evaluation of therapeutic targets and the development of gene therapies. Their precision and reliability facilitate high-throughput screenings, functional studies, and the validation of drug targets, making them suitable for applications ranging from basic research to drug discovery.
Compared to alternative products, such as traditional knockdown systems utilizing RNA interference, ZNF485 Gene Knockout Cell Lines offer permanent and heritable modifications to the genome, leading to more stable experimental outcomes. This durability ensures that the observed effects are robust and reproducible over time.
The value of ZNF485 Gene Knockout Cell Lines extends to researchers and clinicians looking to deepen their understanding of genetic mechanisms and explore innovative therapeutic strategies. The utility of these cell lines in generating relevant in vitro models significantly accelerates the pace of research, ultimately benefiting the development of novel treatment approaches.
Our company specializes in creating high-quality biological products, leveraging cutting-edge gene editing technologies and offering comprehensive support to our users, ensuring that they have the necessary tools to drive impactful research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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