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ZNF480 Knockout Cell Lines

Gene: ZNF480

Official Full Name: zinc finger protein 480provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23678 ZNF480 Knockout cell line (HeLa) Human ZNF480 1:3~1:6 Negative Online Inquiry
KO23679 ZNF480 Knockout cell line (HCT 116) Human ZNF480 1:2~1:4 Negative Online Inquiry
KO23680 ZNF480 Knockout cell line (HEK293) Human ZNF480 1:3~1:6 Negative Online Inquiry
KO23681 ZNF480 Knockout cell line (A549) Human ZNF480 1:3~1:4 Negative Online Inquiry

Background

ZNF480 Gene Knockout Cell Lines represent a groundbreaking advancement in genetic research and functional genomics, characterized by their targeted disruption of the ZNF480 gene through CRISPR/Cas9 technology. These cell lines are integral tools for studying the biological roles of ZNF480, a zinc finger transcription factor implicated in various cellular processes including differentiation, proliferation, and apoptosis. By creating precise gene knockouts, researchers can elucidate the functional consequences of ZNF480 absence, offering insights into its potential association with diseases, particularly in oncology and developmental biology.

The key function of ZNF480 Gene Knockout Cell Lines lies in their ability to serve as an experimental platform for investigating gene function in vitro. The knockout mechanism utilizes a highly efficient CRISPR/Cas9 system, enabling selective editing of the genome with minimal off-target effects. This precision allows for reliable studies on how the disruption of ZNF480 alters cellular behavior, signaling pathways, and gene expression profiles.

From a scientific standpoint, these cell lines hold significant potential in both basic research and clinical applications. In research settings, they provide a model for developing targeted therapies and understanding disease mechanisms, while in clinical contexts, they can aid in drug discovery and therapeutic interventions aimed at modulating ZNF480 activity. The ability to study this gene’s function in normal and pathological states positions these cell lines as invaluable assets in translational research.

Compared to traditional methods such as siRNA or shRNA, ZNF480 Gene Knockout Cell Lines offer superior specificity and stability in gene expression modulation. These cell lines allow for long-term studies without the complications associated with transient gene knockdown, providing a more consistent and reliable model for research.

Researchers, clinicians, and biotechnology companies will find ZNF480 Gene Knockout Cell Lines appealing due to their versatility, reliability, and the depth of data they can generate. The understanding gained from using these cell lines could pave the way for novel therapeutic strategies targeting diseases linked to ZNF480 dysregulation.

At [Your Company Name], we pride ourselves on our commitment to innovation and excellence in developing cutting-edge biological products. Our expertise in gene editing technology has enabled us to offer precise, reliable tools that drive meaningful scientific advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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