Gene: ZNF471
Official Full Name: zinc finger protein 471provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12210 | ZNF471 Knockout cell line (HEK293) | Human | ZNF471 | 1:3~1:6 | Negative | Online Inquiry |
ZNF471 Gene Knockout Cell Lines represent a revolutionary tool in the realm of genetic research and functional genomics. These cell lines have been specifically engineered to have a complete knockout of the ZNF471 gene, a crucial component implicated in various biological processes, including transcription regulation, cellular differentiation, and developmental biology. By utilizing advanced gene-editing technologies, such as CRISPR/Cas9, scientists can explore the physiological and pathological roles of ZNF471 with unprecedented precision.
The primary function of these knockout cell lines lies in their ability to facilitate the investigation of ZNF471's roles in cellular mechanisms. Researchers can examine changes in gene expression, protein interactions, and cellular behavior that occur in the absence of ZNF471. This makes the cell lines invaluable for elucidating gene function, understanding disease pathways, and developing therapeutic strategies. Moreover, the knockouts can serve as robust models for studying disorders associated with dysregulated gene activity, such as certain cancers or developmental syndromes.
In terms of scientific significance, ZNF471 gene knockout cell lines are applicable in both research laboratories and clinical settings. They provide a platform for drug discovery, allowing for the identification of potential targets and the evaluation of drug efficacy in a controlled environment. Their use helps bridge the gap between basic research and translational applications, ultimately contributing to advancements in personalized medicine.
Compared to alternative methods of gene silencing, such as RNA interference or transient transfection approaches, the ZNF471 knockout cell lines offer several advantages. They achieve stable genome editing, ensuring long-term expression of the knockout phenotype, and facilitate reproducibility in experimental design. Additionally, these cell lines can be adapted for high-throughput screening processes, maximizing efficiency and throughput compared to traditional methods.
The value of ZNF471 Gene Knockout Cell Lines is profound for researchers and clinicians aiming to deepen their understanding of genetic function and disease mechanisms. By providing a reliable and innovative resource for studying the ZNF471 gene, they empower scientific discovery and the development of novel therapeutic interventions.
With a commitment to excellence in the field of cellular and molecular biology, our company employs cutting-edge methodologies and a deep understanding of genetic research to deliver products that support and enhance scientific exploration. Our expertise ensures that you receive high-quality, rigorously validated biological products that cater to the evolving needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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