Gene: ZNF460
Official Full Name: zinc finger protein 460provided by HGNC
Gene Summary: Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31508 | ZNF460 Knockout cell line (HCT 116) | Human | ZNF460 | 1:2~1:4 | Negative | Online Inquiry |
KO31509 | ZNF460 Knockout cell line (HEK293) | Human | ZNF460 | 1:3~1:6 | Negative | Online Inquiry |
KO31510 | ZNF460 Knockout cell line (A549) | Human | ZNF460 | 1:3~1:4 | Negative | Online Inquiry |
ZNF460 Gene Knockout Cell Lines are pioneering tools in molecular biology designed for the targeted study of the ZNF460 gene, which is implicated in various cellular processes, including gene regulation and chromatin remodeling. By employing CRISPR/Cas9 technology, these cell lines ensure specific deletion of the ZNF460 gene, allowing researchers to observe resultant phenotypic changes and gain deeper insights into its functional roles.
The primary function of ZNF460 Gene Knockout Cell Lines is to facilitate the investigation of the gene's involvement in cellular pathways, disease mechanisms, and therapeutic responses. By creating a definitive model lacking the ZNF460 gene, researchers can elucidate its impact on gene expression, signaling pathways, and interactions with other proteins. This provides a valuable platform for investigating potential targets for drug development or therapeutic intervention.
Scientifically, ZNF460 plays a vital role in understanding various diseases, such as cancer and neurodegenerative disorders. The ability to generate knockout models accelerates advancements in basic research and offers potential translational applications. These cell lines serve as crucial resources for academic institutions and pharmaceutical companies alike, aiding in the development of novel therapies and guiding clinical research.
The primary advantages of ZNF460 Gene Knockout Cell Lines over traditional methods, such as RNA interference, are their permanence and specificity. Once the gene is knocked out, the effect is stable across generations of cells, allowing for long-term studies without the variability associated with transient knockdown experiments. Moreover, the efficiency and precision of CRISPR/Cas9 ensure that off-target effects are minimized, thus enhancing the reliability of experimental data.
For researchers and clinicians, these cell lines represent an invaluable asset that simplifies the study of complex biological processes and disease models. With ZNF460 Gene Knockout Cell Lines, users have the opportunity to contribute to groundbreaking research and potentially advance therapeutic strategies in disease management.
Our company specializes in the development and provision of high-quality biological products, with a focus on facilitating scientific discovery and innovation. With robust expertise in molecular biology and a commitment to scientific excellence, we aim to support the research community with reliable tools that enhance their capabilities in exploring genetic functions and therapeutic potentials.
Please note that all services are for research use only. Not intended for any clinical use.
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