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ZNF404 Knockout Cell Lines

Gene: ZNF404

Official Full Name: zinc finger protein 404provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20761 ZNF404 Knockout cell line (HEK293) Human ZNF404 1:3~1:6 Negative Online Inquiry
KO20762 ZNF404 Knockout cell line (A549) Human ZNF404 1:3~1:4 Negative Online Inquiry

Background

ZNF404 Gene Knockout Cell Lines are meticulously developed cellular models that have undergone targeted gene editing to disrupt the ZNF404 gene's function. This innovative product enables researchers to investigate the gene's roles in various physiological and pathological processes. The knockout is achieved through precise gene-editing techniques, such as CRISPR-Cas9, which allow for the complete ablation of ZNF404 expression. By eliminating this gene, scientists can glean insights into its contributions to cellular mechanisms, including gene regulation, signal transduction, and developmental pathways.

The utility of ZNF404 Gene Knockout Cell Lines extends into both research and clinical applications. In research settings, these cell lines are invaluable for exploring the consequences of ZNF404 disruption on cellular behavior, gene expression profiles, and interaction networks. This is especially relevant in fields such as cancer research and neurobiology, where ZNF404 may play a role in disease progression or symptom manifestation. Clinically, these models pave the way for studies aimed at identifying therapeutic targets and developing associated interventions.

Compared to traditional cell lines that express ZNF404, these knockout models offer a distinct advantage by providing a clearer understanding of gene function devoid of confounding variables. The specificity of the knockout allows for more targeted studies, thereby improving data reliability and relevance.

For researchers and clinicians, ZNF404 Gene Knockout Cell Lines represent a powerful tool that facilitates discovery and innovation. Their ability to unravel the complexities of gene functions not only accelerates the pace of research but also enhances the development of targeted therapies.

Our company, leveraging years of expertise in genetic engineering and cell line development, is committed to providing high-quality and reliable biological products that empower the scientific community. With a focus on precision and innovation, we continuously strive to support researchers in their quest to advance knowledge and improve health outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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