Gene: ZNF396
Official Full Name: zinc finger protein 396provided by HGNC
Gene Summary: Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of DNA-templated transcription. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21254 | ZNF396 Knockout cell line (HeLa) | Human | ZNF396 | 1:3~1:6 | Negative | Online Inquiry |
KO21255 | ZNF396 Knockout cell line (HEK293) | Human | ZNF396 | 1:3~1:6 | Negative | Online Inquiry |
ZNF396 Gene Knockout Cell Lines are sophisticated biological tools developed to facilitate the in-depth study of the ZNF396 gene, a member of the zinc finger protein family, which plays a critical role in various cellular processes including transcription regulation and signal transduction. These knockout cell lines are engineered through CRISPR-Cas9 technology, allowing for precise gene modifications that result in complete loss of ZNF396 expression. By creating a controlled genetic environment, researchers can investigate the gene's specific functions, interactions, and contributions to cellular physiology and pathology.
The principal mechanism underlying ZNF396 knockout involves the introduction of double-strand breaks in the target gene, leading to insertions or deletions that disrupt gene function. This approach not only elucidates the role of ZNF396 in fundamental biological pathways but also aids in the identification of downstream effects on gene networks and cellular responses. The ability to study these knockout cell lines is paramount for gaining insights into diseases where ZNF396 may play a pivotal role, including certain cancers and metabolic disorders.
The scientific importance of ZNF396 Gene Knockout Cell Lines extends to both basic research and clinical applications, particularly in drug development and therapeutic interventions. Compared to traditional knockout methods, our cell lines provide a higher degree of specificity and reliability, ensuring that results are reproducible and biologically relevant. This precision significantly enhances research quality compared to other available models, such as vector-based knockdowns or random mutagenesis.
For researchers and clinicians aiming to deepen their understanding of gene function in disease contexts, ZNF396 Gene Knockout Cell Lines are invaluable resources. They empower users to explore innovative avenues for therapeutic strategies and deliver more effective, targeted treatments. Our commitment to excellence in biological product development, backed by rigorous scientific validation and comprehensive technical support, positions us as leaders in providing high-quality research tools. Together, we contribute to advancing knowledge in genetics and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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