Gene: ZNF385B
Official Full Name: zinc finger protein 385Bprovided by HGNC
Gene Summary: Enables p53 binding activity. Involved in intrinsic apoptotic signaling pathway by p53 class mediator. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22008 | ZNF385B Knockout cell line (HCT 116) | Human | ZNF385B | 1:2~1:4 | Negative | Online Inquiry |
KO22009 | ZNF385B Knockout cell line (HEK293) | Human | ZNF385B | 1:3~1:6 | Negative | Online Inquiry |
ZNF385B Gene Knockout Cell Lines are engineered cellular models specifically designed to lack the functional ZNF385B gene, which is known for its role in transcriptional regulation and potential involvement in various biological pathways, including cell proliferation and differentiation. These knockout cell lines are invaluable tools for researchers studying gene function, signaling pathways, and the mechanistic aspects of disease.
The primary function of ZNF385B Gene Knockout Cell Lines is to enable scientists to investigate the phenotypic consequences of ZNF385B deletion. By using CRISPR-Cas9 technology, these cell lines are created through precise genome editing, allowing for the effective study of gene interactions and alterations in cellular behavior. Researchers can assess changes in pathways related to cellular growth, apoptosis, and response to therapeutic agents, thus providing insights into the gene's role in health and disease.
In terms of scientific importance, these cell lines have significant applications in both research and clinical settings. They serve as vital models for cancer research, neurobiology, and regenerative medicine, allowing for the exploration of ZNF385B's implications in various pathologies. By understanding the gene's contribution to disease mechanisms, researchers can identify novel therapeutic targets and develop innovative treatment strategies.
Distinct from traditional cell lines, ZNF385B Gene Knockout Cell Lines offer specific advantages, including high reproducibility, robust performance in assays, and the ability to model gene interactions under controlled conditions. Additionally, these lines facilitate the exploration of compensatory mechanisms that may arise upon ZNF385B deletion, providing a completer understanding of gene function.
For researchers and clinicians aiming to advance their studies, these knockout cell lines provide a valuable resource that enhances the depth of investigation into gene function and disease mechanisms. With our company's extensive expertise in gene editing technologies and cellular model development, we are committed to providing high-quality biological tools that accelerate scientific discovery and contribute to meaningful advancements in the field.
Please note that all services are for research use only. Not intended for any clinical use.
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