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ZNF383 Knockout Cell Lines

Gene: ZNF383

Official Full Name: zinc finger protein 383provided by HGNC

Gene Summary: The protein encoded by this gene is a KRAB-related zinc finger protein that inhibits the transcription of some MAPK signaling pathway genes. The repressor activity resides in the KRAB domain of the encoded protein. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12277 ZNF383 Knockout cell line (HeLa) Human ZNF383 1:3~1:6 Negative Online Inquiry
KO12278 ZNF383 Knockout cell line (HCT 116) Human ZNF383 1:2~1:4 Negative Online Inquiry
KO12279 ZNF383 Knockout cell line (HEK293) Human ZNF383 1:3~1:6 Negative Online Inquiry
KO12280 ZNF383 Knockout cell line (A549) Human ZNF383 1:3~1:4 Negative Online Inquiry

Background

ZNF383 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the ZNF383 gene. This gene encodes a zinc finger protein that plays a crucial role in various biological processes, including regulation of gene expression, cellular differentiation, and development. By utilizing CRISPR/Cas9 technology, these cell lines enable researchers to systematically examine the effects of ZNF383 deficiency, facilitating a deeper understanding of its functions in health and disease.

The primary mechanism behind these knockout cell lines involves targeted genome editing, which effectively disrupts the ZNF383 gene. The resulting cell lines provide a unique platform for studying cellular pathways and validating the gene’s involvement in various physiological and pathological conditions, such as cancer and neurological disorders. These models are invaluable for researchers aiming to delineate ZNF383's role in gene regulatory networks or to identify potential therapeutic targets for diseases associated with its dysregulation.

Scientifically, ZNF383 knockout cell lines possess significant applications in both academic research and pharmaceutical development. They facilitate high-throughput screening for small molecules that could restore normal function or serve as inhibitors of disease pathways influenced by ZNF383. As more research elucidates the gene's contributions to specific cellular processes, these cell lines will support advancements in personalized medicine and targeted therapies.

What sets ZNF383 Gene Knockout Cell Lines apart from alternatives is their validated performance, ease of use, and the comprehensive support provided throughout their application. Our thorough characterization ensures that researchers receive reliable and consistent results, which is essential in experimental designs.

For researchers and clinicians seeking to push the boundaries of gene function studies and therapeutic interventions, ZNF383 Gene Knockout Cell Lines offer an unmatched resource. Our company specializes in the development of high-quality biological models tailored to the research community’s needs, supported by years of expertise in genome editing technology and cell line development.

Please note that all services are for research use only. Not intended for any clinical use.

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