Gene: ZNF346
Official Full Name: zinc finger protein 346provided by HGNC
Gene Summary: The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29126 | ZNF346 Knockout cell line (HeLa) | Human | ZNF346 | 1:3~1:6 | Negative | Online Inquiry |
KO29127 | ZNF346 Knockout cell line (HCT 116) | Human | ZNF346 | 1:2~1:4 | Negative | Online Inquiry |
KO29128 | ZNF346 Knockout cell line (HEK293) | Human | ZNF346 | 1:3~1:6 | Negative | Online Inquiry |
KO29129 | ZNF346 Knockout cell line (A549) | Human | ZNF346 | 1:3~1:4 | Negative | Online Inquiry |
ZNF346 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF346 gene has been systematically disrupted, providing a powerful tool for researchers studying gene function, signaling pathways, and disease mechanisms. The ZNF346 gene encodes a zinc-finger protein that is involved in various cellular processes, including transcriptional regulation, cell proliferation, and differentiation. By utilizing CRISPR/Cas9 technology for the knockout process, these cell lines enable precise gene editing to study the phenotypic and functional consequences of ZNF346 loss, allowing scientists to dissect its role in various biological contexts.
The primary function of ZNF346 Gene Knockout Cell Lines is to facilitate the investigation of gene interactions and regulatory networks, particularly in studies related to cancer biology and genetic disorders. By analyzing the phenotypic changes associated with ZNF346 gene disruption, researchers can uncover the molecular pathways influenced by this gene, contributing to a deeper understanding of its biological significance and potential therapeutic targets.
In the realm of scientific research and clinical applications, these knockout cell lines are invaluable for functional genomics studies, drug discovery, and personalized medicine. They provide a robust platform for testing the efficacy of potential drug candidates and elucidating the biological mechanisms underpinning disease progression. Furthermore, ZNF346's association with various diseases makes its knockout cell lines critical for preclinical studies aimed at identifying novel therapeutic interventions.
What sets ZNF346 Gene Knockout Cell Lines apart from other genetic models is their high specificity and reliability, achieved through advanced editing techniques. This specificity translates into more accurate experimental outcomes compared to conventional methods that may yield off-target effects. Additionally, researchers benefit from thorough characterization and validation, ensuring that these cell lines serve as trustworthy resources for scientific inquiry.
Investing in ZNF346 Gene Knockout Cell Lines means accessing a cutting-edge tool that aligns with the needs of today's research community. These cell lines offer the potential to unlock new understanding in fields ranging from molecular biology to translational medicine, thereby paving the way for discoveries that could lead to significant advancements in health and disease treatment. Our company prides itself on delivering high-quality biological products backed by rigorous scientific validation and an ongoing commitment to innovation in gene editing technologies.
Please note that all services are for research use only. Not intended for any clinical use.
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