Gene: ZNF317
Official Full Name: zinc finger protein 317provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12305 | ZNF317 Knockout cell line (HeLa) | Human | ZNF317 | 1:3~1:6 | Negative | Online Inquiry |
KO12306 | ZNF317 Knockout cell line (HCT 116) | Human | ZNF317 | 1:2~1:4 | Negative | Online Inquiry |
KO12307 | ZNF317 Knockout cell line (HEK293) | Human | ZNF317 | 1:3~1:6 | Negative | Online Inquiry |
KO12308 | ZNF317 Knockout cell line (A549) | Human | ZNF317 | 1:3~1:4 | Negative | Online Inquiry |
ZNF317 Gene Knockout Cell Lines represent a pivotal advancement in the realm of molecular biology and genetic research. These engineered cell lines have been meticulously designed to contain a targeted deletion of the ZNF317 gene, which encodes a zinc finger protein implicated in various cellular processes, including transcription regulation, cellular differentiation, and apoptotic pathways. By silencing this gene, researchers can elucidate its specific functions and contributions to normal physiology as well as disease pathology.
The key mechanism behind these cell lines lies in the use of advanced CRISPR/Cas9 technology, which enables precise editing of the genomic DNA. The targeted knockout approach allows for a clear understanding of the ZNF317 gene's influence on cellular behavior, gene expression, and signaling pathways. This functional study is critical for discerning the role of ZNF317 in diseases such as cancer, where aberrant gene expression frequently disrupts normal cellular function.
Scientifically, the ZNF317 Gene Knockout Cell Lines hold immense importance in both fundamental and applied research. In a clinical setting, they serve as invaluable tools for drug discovery, providing insights into potential therapeutic targets and the mechanism of action of novel compounds. The cell lines can also facilitate studies on gene therapy applications, where understanding the knockout effects is essential for developing effective treatments.
Compared to alternative products, ZNF317 Gene Knockout Cell Lines stand out due to their high specificity and efficiency in gene editing, coupled with the reliability of the CRISPR system. Unlike traditional methods that may yield inconclusive results or require extensive validation, our knockout lines deliver consistent and reproducible data, adding to the robustness of experimental outcomes.
For researchers, clinicians, and biotechnology companies, the ZNF317 Gene Knockout Cell Lines are invaluable assets that accelerate discovery and innovation in genetic research. By allowing the dissection of complex gene functions, they open avenues for novel therapeutic strategies and biomarker identification.
Leveraging years of expertise in gene editing and cell line development, our company is committed to providing high-quality biological products that drive scientific breakthroughs and enhance research capabilities for our clients.
Please note that all services are for research use only. Not intended for any clinical use.
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