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ZNF296 Knockout Cell Lines

Gene: ZNF296

Official Full Name: zinc finger protein 296provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of dendrite development; regulation of transcription by RNA polymerase II; and spermatogenesis. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23652 ZNF296 Knockout cell line (HeLa) Human ZNF296 1:3~1:6 Negative Online Inquiry
KO23653 ZNF296 Knockout cell line (HCT 116) Human ZNF296 1:2~1:4 Negative Online Inquiry
KO23654 ZNF296 Knockout cell line (HEK293) Human ZNF296 1:3~1:6 Negative Online Inquiry
KO23655 ZNF296 Knockout cell line (A549) Human ZNF296 1:3~1:4 Negative Online Inquiry

Background

ZNF296 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the role of the ZNF296 gene, which encodes a zinc finger protein implicated in various biological processes, including gene regulation and cellular development. These knockout cell lines are created using CRISPR-Cas9 technology, enabling precise deletion of the ZNF296 gene, allowing researchers to investigate the downstream effects of its absence on cellular phenotype, signaling pathways, and gene expression.

The key mechanism underlying the functionality of ZNF296 knockout cell lines lies in their ability to mimic the loss-of-function scenarios found in diseases associated with aberrant zinc finger protein activities. This provides an invaluable platform for researchers to elucidate the biological mechanisms and functional ramifications of ZNF296 in processes such as oncogenesis, immune response, and neurodevelopment. By employing these cell lines in laboratory settings, scientists can also screen for potential therapeutic targets or drugs that can ameliorate the effects of ZNF296-related dysfunctions.

The scientific importance of ZNF296 knockout cell lines extends beyond basic research; they hold significant promise in clinical applications, including drug discovery and development of precision therapies tailored to specific genetic backgrounds. Unlike conventional cell lines, these knockout models provide a more accurate reflection of disease mechanisms, enhancing the relevance of experimental findings.

What sets our ZNF296 Gene Knockout Cell Lines apart from alternatives is the painstaking effort taken to ensure high knockout efficiency and the comprehensive validation of the genetic modifications. This guarantees that researchers are equipped with reliable and reproducible tools for their studies. Additionally, our commitment to providing thorough technical support and protocol optimization further enhances the user experience, facilitating smoother experiments and more robust outcomes.

By integrating cutting-edge technology with an unwavering focus on quality and reliability, our company stands as a leader in providing innovative biological products. Researchers and clinicians can trust in our expertise and product offerings to propel their investigations or therapeutic developments effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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