Gene: ZNF274
Official Full Name: zinc finger protein 274provided by HGNC
Gene Summary: This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31527 | ZNF274 Knockout cell line (HeLa) | Human | ZNF274 | 1:3~1:6 | Negative | Online Inquiry |
KO31528 | ZNF274 Knockout cell line (HCT 116) | Human | ZNF274 | 1:2~1:4 | Negative | Online Inquiry |
KO31529 | ZNF274 Knockout cell line (HEK293) | Human | ZNF274 | 1:3~1:6 | Negative | Online Inquiry |
KO31530 | ZNF274 Knockout cell line (A549) | Human | ZNF274 | 1:3~1:4 | Negative | Online Inquiry |
ZNF274 Gene Knockout Cell Lines represent a groundbreaking tool for researchers seeking to unravel the complexities of gene function and regulation. At its core, this product consists of genetically engineered cell lines in which the ZNF274 gene has been systematically disrupted. This powerful technique, known as gene knockout, allows scientists to observe the cellular and molecular consequences of the absence of ZNF274, providing insights into its role in various biological processes and disease states.
The ZNF274 protein is a member of the zinc finger protein family, which is known for its role in transcriptional regulation and chromatin remodeling. By eliminating ZNF274 expression, researchers can elucidate its impact on gene expression profiles, signal transduction pathways, and cellular differentiation. This cell line can be particularly valuable in studying disorders linked to dysregulated transcriptional control, such as cancer and developmental diseases.
In terms of scientific importance and applications, ZNF274 Gene Knockout Cell Lines offer a unique platform for gene function analysis, drug discovery, and personalized medicine research. Their ability to mimic pathological conditions in vitro provides critical data that can accelerate the translational aspect of research into clinical therapies. Compared to other gene editing methods, such as CRISPR/Cas9, our knockout cell lines provide a stable and readily usable resource, significantly reducing the time and complexity of experimental setups.
What sets our ZNF274 Gene Knockout Cell Lines apart is the stringent validation they undergo, ensuring reliability and reproducibility of results. Researchers and clinicians can trust these cell lines to deliver high-quality data necessary for advancing their studies. Furthermore, they are compatible with a wide range of assays, including but not limited to, gene expression analysis, signaling assays, and phenotypic screening.
With years of expertise in developing and optimizing biological tools, our company is committed to providing top-tier products that empower the scientific community in their quest to unlock new discoveries. The ZNF274 Gene Knockout Cell Lines are not just another research tool; they are a key to understanding the intricate web of genetic regulation and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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