Home / ZNF236 Knockout Cell Lines

ZNF236 Knockout Cell Lines

Gene: ZNF236

Official Full Name: zinc finger protein 236provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to glucose stimulus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34473 ZNF236 Knockout cell line (HeLa) Human ZNF236 1:3~1:6 Negative Online Inquiry
KO34474 ZNF236 Knockout cell line (HCT 116) Human ZNF236 1:2~1:4 Negative Online Inquiry
KO34475 ZNF236 Knockout cell line (HEK293) Human ZNF236 1:3~1:6 Negative Online Inquiry
KO34476 ZNF236 Knockout cell line (A549) Human ZNF236 1:3~1:4 Negative Online Inquiry

Background

ZNF236 Gene Knockout Cell Lines are meticulously engineered cellular models specifically designed to elucidate the function of the ZNF236 gene, which encodes a zinc-finger protein involved in various cellular processes, including transcriptional regulation and cell cycle control. These cell lines have been generated using advanced CRISPR-Cas9 genome editing technologies, resulting in precise disruption of the ZNF236 gene. By systematically knocking out this gene, researchers can investigate the resultant phenotypic changes and molecular pathways impacted by its absence, offering valuable insight into gene function and regulation.

The key mechanism underlying these knockout cell lines involves the introduction of targeted double-strand breaks in the DNA sequence of the ZNF236 gene, followed by cellular repair processes that lead to insertion or deletion mutations. This approach allows for the gain of function and loss of function studies, which are critical for understanding gene functions and their roles in various biological contexts, including disease models.

Scientifically, the ZNF236 gene knockout cell lines have significant applications in both basic research and clinical settings, including studies on oncogenesis, developmental biology, and gene expression regulation. They serve as indispensable tools for drug discovery, enabling the identification of novel therapeutic targets or understanding drug resistance mechanisms.

What sets our ZNF236 Gene Knockout Cell Lines apart from alternatives is their high specificity, reproducibility, and the comprehensive validation of the knockout efficiency. This ensures that researchers can confidently attribute observed changes to the disruption of the ZNF236 gene specifically.

For researchers and clinicians alike, the value of using these cell lines extends beyond mere experimentation; they provide a robust platform for translating basic research findings into potential clinical applications, ultimately enhancing the development of targeted therapies.

Our company prides itself on its commitment to advancing scientific research through the provision of high-quality biological products. With a proven expertise in cell line development and genetic engineering, we ensure that our offerings meet the rigorous demands of the scientific community, fostering innovation and discovery in research laboratories worldwide.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.