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ZNF221 Knockout Cell Lines

Gene: ZNF221

Official Full Name: zinc finger protein 221provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34645 ZNF221 Knockout cell line (HCT 116) Human ZNF221 1:2~1:4 Negative Online Inquiry
KO34646 ZNF221 Knockout cell line (HEK293) Human ZNF221 1:3~1:6 Negative Online Inquiry
KO34647 ZNF221 Knockout cell line (A549) Human ZNF221 1:3~1:4 Negative Online Inquiry

Background

ZNF221 Gene Knockout Cell Lines represent a powerful tool in molecular biology, specifically designed to facilitate the study of the ZNF221 gene and its functional implications in cellular processes. These genetically modified cell lines are created using CRISPR-Cas9 technology to precisely edit the ZNF221 gene, resulting in its knockout. This loss-of-function model allows researchers to investigate the role of ZNF221 in various biological contexts, such as gene regulation, cell differentiation, and tumorigenesis.

The key function of these knockout cell lines lies in their ability to provide insight into the ZNF221 gene's impact on cellular behavior. By examining the physiological and biochemical changes that occur in ZNF221-deficient cells, scientists can uncover the gene's contributions to key pathways involved in cancer progression and other diseases. The knockout model also enables high-throughput screening of potential therapeutic targets, enhancing drug discovery efforts.

The scientific importance of ZNF221 Gene Knockout Cell Lines extends to their applications in both basic and translational research. Understanding ZNF221's role in gene regulatory networks can pave the way for novel therapeutic strategies aimed at manipulating gene expression for therapeutic benefit. These cell lines serve as a reliable platform for investigating gene function, biomarker discovery, and the development of personalized medicine approaches.

What sets ZNF221 Gene Knockout Cell Lines apart from conventional alternatives is their ease of use and specificity due to the advanced CRISPR technology employed. Unlike older methods that often resulted in off-target effects, CRISPR allows for more precise modifications, ensuring high fidelity in experimental results. This precision not only improves the reliability of findings but also accelerates the timelines for research and drug development.

For researchers and clinicians seeking to delve deeper into the molecular underpinnings of diseases associated with the ZNF221 gene, these knockout cell lines offer unmatched value. Their unique capabilities provide key insights that could lead to breakthroughs in understanding complex biological systems and developing innovative therapies.

Our company prides itself on delivering cutting-edge genetic materials and tools tailored for the research community. With a strong foundation in molecular biology and a commitment to advancing scientific discovery, we are dedicated to providing high-quality products that empower researchers to achieve their scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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