Gene: ZNF2
Official Full Name: zinc finger protein 2provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12351 | ZNF2 Knockout cell line (HeLa) | Human | ZNF2 | 1:3~1:6 | Negative | Online Inquiry |
KO12352 | ZNF2 Knockout cell line (HCT 116) | Human | ZNF2 | 1:2~1:4 | Negative | Online Inquiry |
KO12353 | ZNF2 Knockout cell line (HEK293) | Human | ZNF2 | 1:3~1:6 | Negative | Online Inquiry |
KO12354 | ZNF2 Knockout cell line (A549) | Human | ZNF2 | 1:3~1:4 | Negative | Online Inquiry |
ZNF2 Gene Knockout Cell Lines are specialized cellular models in which the ZNF2 gene has been systematically disrupted or deleted, allowing the study of gene function and associated biological pathways in a controlled experimental setup. These knockout cell lines enable researchers to assess the role of the ZNF2 gene in various cellular processes, including gene regulation, signal transduction, and developmental biology. By eliminating the expression of ZNF2, scientists can utilize these cell lines to explore phenotypic changes, protein interactions, and the gene's contribution to disease mechanisms, particularly in oncological and neurological contexts.
The key mechanism underpinning these cell lines involves clustered regularly interspaced short palindromic repeats (CRISPR) technology, which facilitates precise editing of genomic sequences. This innovation allows for high efficiency and specificity in creating gene knockouts, minimizing off-target effects that often complicate genetic studies. The resulting cell lines serve as vital tools in elucidating the biological functions of ZNF2, providing insights into its potential as a therapeutic target.
Scientifically, ZNF2 gene knockout cell lines are pivotal in research settings where understanding the gene's contributions to cellular behavior is necessary. These models can be employed in drug screening, disease modeling, and biomarker discovery, making them invaluable assets to both academic and clinical researchers. By offering a reliable platform for investigations into gene function, these cell lines enhance the capacity for translational research, accelerating the development of targeted therapies.
Compared to alternative approaches, such as RNA interference or transgenic systems, ZNF2 knockout cell lines offer greater specificity and stability, allowing researchers to observe the long-term effects of gene disruption without the confounding variables inherent in transient knockdown strategies. These advantages make ZNF2 knockout cell lines an optimal choice for studies examining gene functions in a variety of biological contexts.
For researchers and clinicians, investing in ZNF2 gene knockout cell lines is crucial for advancing scientific inquiry and therapeutic development. With reliable and reproducible experimental outcomes, these cell lines provide high-quality models that can lead to significant breakthroughs in understanding genetic and cancer-related disorders.
At our company, we pride ourselves on offering cutting-edge biological products supported by extensive research and development. Our expertise in gene editing technologies ensures that our ZNF2 knockout cell lines are of the highest quality, empowering researchers to unlock the mysteries of genetic regulation and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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