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ZNF14 Knockout Cell Lines

Gene: ZNF14

Official Full Name: zinc finger protein 14provided by HGNC

Gene Summary: The protein encoded by this gene contains a zinc finger and a Kruppel-associated box (KRAB) domain. KRAB domain is known to be involved in the transcriptional repression of a number of zinc finger proteins. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34740 ZNF14 Knockout cell line (HeLa) Human ZNF14 1:3~1:6 Negative Online Inquiry
KO34741 ZNF14 Knockout cell line (HCT 116) Human ZNF14 1:2~1:4 Negative Online Inquiry
KO34742 ZNF14 Knockout cell line (HEK293) Human ZNF14 1:3~1:6 Negative Online Inquiry
KO34743 ZNF14 Knockout cell line (A549) Human ZNF14 1:3~1:4 Negative Online Inquiry

Background

ZNF14 Gene Knockout Cell Lines represent a groundbreaking advancement in genetic research, specifically designed to facilitate the investigation of the ZNF14 gene's role in cellular processes and disease mechanisms. These cell lines have been meticulously engineered to disable the ZNF14 gene, offering researchers a powerful tool to explore gene function, regulatory pathways, and potential therapeutic targets linked to this important zinc finger protein.

The primary function of the ZNF14 Gene Knockout Cell Lines lies in their ability to model the absence of ZNF14, thereby enabling the study of its contributions to gene expression regulation, cell differentiation, and other vital biological processes. Mechanistically, the knockout allows scientists to discern how the loss of ZNF14 influences cellular phenotypes, including changes in transcriptional profiles and responses to stressors. This can be particularly relevant for exploring pathways implicated in cancer, autoimmune diseases, and developmental disorders.

The scientific importance of these cell lines extends into both basic and applied research. In clinical settings, they can be utilized to evaluate the efficacy of experimental drugs or gene therapies aiming to modulate gene expression, offering insights into potential interventions for disorders linked to dysregulated ZNF14 activity. Furthermore, these knockout models can simplify the elucidation of complex genetic interactions, making them invaluable for gene mapping and functional genomics studies.

Compared to traditional methods for gene silencing, such as siRNA or CRISPR interference, the ZNF14 Gene Knockout Cell Lines provide a stable and consistent platform that permits long-term observation of phenotypic outcomes and experimental reproducibility. This robust advantages facilitate more reliable data collection and innovative research design.

For researchers, clinicians, and institutions seeking to advance their understanding of gene function and disease pathways, ZNF14 Gene Knockout Cell Lines are an essential asset that can propel discoveries and accelerate the pace of translational science. Our commitment to delivering high-quality biological products is rooted in our extensive expertise in gene editing technologies and cellular model development, ensuring that every product meets the rigorous standards of modern research.

Please note that all services are for research use only. Not intended for any clinical use.

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