Gene: ZNF124
Official Full Name: zinc finger protein 124provided by HGNC
Gene Summary: This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34624 | ZNF124 Knockout cell line (HeLa) | Human | ZNF124 | 1:3~1:6 | Negative | Online Inquiry |
KO34625 | ZNF124 Knockout cell line (HCT 116) | Human | ZNF124 | 1:2~1:4 | Negative | Online Inquiry |
KO34626 | ZNF124 Knockout cell line (HEK293) | Human | ZNF124 | 1:3~1:6 | Negative | Online Inquiry |
KO34627 | ZNF124 Knockout cell line (A549) | Human | ZNF124 | 1:3~1:4 | Negative | Online Inquiry |
ZNF124 Gene Knockout Cell Lines are a pioneering tool developed for the precise study of gene function and regulation. These genetically modified cell lines are engineered to have a complete knockout of the ZNF124 gene, a key regulator in numerous biological processes, including cellular differentiation and proliferation. By deactivating this gene, researchers can gain valuable insights into its role in various physiological and pathological conditions.
The primary function of ZNF124 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene interactions and pathways. The absence of ZNF124 allows for the investigation of related signaling cascades and provides a controlled environment to test hypotheses regarding gene function. Researchers can assess phenotypic changes, evaluate downstream effects on gene expression, and observe cellular responses, thus advancing our understanding of how ZNF124 contributes to normal biology and disease processes.
Scientifically, these cell lines are crucial for both basic and applied research, including cancer biology, developmental biology, and regenerative medicine. They offer invaluable platforms for drug testing and therapeutic developments by enabling the identification of potential drug targets and mechanisms of action. In clinical settings, understanding the implications of ZNF124 dysfunction may lead to novel interventions in diseases associated with altered gene expression.
What sets our ZNF124 Gene Knockout Cell Lines apart from alternatives is their high specificity and reliability, as they are derived from rigorously validated protocols ensuring consistent genetic modifications. Additionally, they are produced in facilities compliant with the highest standards of quality control, making them suitable for sensitive research applications.
The value of ZNF124 Gene Knockout Cell Lines for researchers and clinicians cannot be overstated; they provide an essential resource for dissecting complex gene functions and assessing their relevance in human health. By choosing our cell lines, users can trust in a product backed by our company's extensive expertise in genetic engineering and cell line development, ensuring they receive high-quality research tools that facilitate groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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