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ZNF12 Knockout Cell Lines

Gene: ZNF12

Official Full Name: zinc finger protein 12provided by HGNC

Gene Summary: This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34752 ZNF12 Knockout cell line (HeLa) Human ZNF12 1:3~1:6 Negative Online Inquiry
KO34753 ZNF12 Knockout cell line (HCT 116) Human ZNF12 1:2~1:4 Negative Online Inquiry
KO34754 ZNF12 Knockout cell line (HEK293) Human ZNF12 1:3~1:6 Negative Online Inquiry
KO34755 ZNF12 Knockout cell line (A549) Human ZNF12 1:3~1:4 Negative Online Inquiry

Background

ZNF12 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the functional study of the ZNF12 gene, which encodes for a zinc finger transcription factor implicated in various biological processes such as cell differentiation, proliferation, and oncogenesis. By utilizing the CRISPR-Cas9 genome editing technology, these cell lines have been precisely modified to eliminate ZNF12 gene expression, thereby allowing researchers to investigate the gene’s specific roles in cellular pathways and disease mechanisms.

The core function of ZNF12 Gene Knockout Cell Lines lies in their ability to provide a controlled environment to dissect the implications of ZNF12 loss on cellular behavior and gene expression profiles. Researchers can assess changes in phenotypic characteristics, signaling pathway alterations, and transcriptional shifts, utilizing techniques such as RNA-seq, Western blot analysis, and flow cytometry to gather comprehensive data. This model is especially crucial in the realms of cancer research and regenerative medicine, where understanding gene contributions can lead to the identification of novel therapeutic targets.

One of the significant advantages of ZNF12 Gene Knockout Cell Lines is their specificity and reproducibility in experiments, which improves data reliability compared to traditional knockdown methods that may produce off-target effects. Furthermore, these cell lines are readily adaptable for high-throughput screening applications, making them suitable for both academic and industrial research settings.

Researchers and clinicians will find value in these cell lines not only for their robustness in elucidating gene function but also for their potential to expedite the development of targeted therapies in oncology and beyond. By offering a reliable tool to dissect gene function, ZNF12 Gene Knockout Cell Lines enhance our understanding of complex biological networks and the underlying mechanisms of disease.

Our company prides itself on being at the forefront of gene editing and cellular modeling technologies, providing high-quality research tools that empower scientists to push the boundaries of biological discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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