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ZNF114 Knockout Cell Lines

Gene: ZNF114

Official Full Name: zinc finger protein 114provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34628 ZNF114 Knockout cell line (HCT 116) Human ZNF114 1:2~1:4 Negative Online Inquiry
KO34629 ZNF114 Knockout cell line (HEK293) Human ZNF114 1:3~1:6 Negative Online Inquiry
KO34630 ZNF114 Knockout cell line (A549) Human ZNF114 1:3~1:4 Negative Online Inquiry

Background

ZNF114 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to disable the ZNF114 gene, which is implicated in various biological processes, including cell differentiation, proliferation, and apoptosis. These cell lines serve as critical tools for understanding the functional role of ZNF114 in human health and disease.

The primary mechanism by which ZNF114 gene knockout cell lines operate involves the use of CRISPR/Cas9 technology, which allows for precise editing of the genome. By creating a disruption in the ZNF114 gene, researchers can observe the resultant phenotypic changes, elucidating the gene's contribution to cellular behavior. This functional assessment is vital for studying gene expression pathways and the molecular mechanisms underlying various diseases, including cancer, where ZNF114 may play a regulatory role.

The scientific importance of these cell lines is evident in their diverse applications in both research and clinical settings. They facilitate high-throughput screening processes for drug discovery, enabling scientists to uncover potential therapeutic targets linked to ZNF114 pathway disruptions. Additionally, these cell lines provide a model for studying the gene's implications in developmental biology and metabolic disorders.

Compared to alternative gene knockout methods, ZNF114 Gene Knockout Cell Lines offer several advantages, including a faster turnaround time, enhanced specificity, and reduced off-target effects, making them superior tools for experimental validity. The robustness of these cell lines ensures consistent results, making them indispensable for researchers aiming for reliable data in their experimental designs.

For researchers and clinicians dedicated to advancing the field of genomics and precision medicine, ZNF114 Gene Knockout Cell Lines present an invaluable resource. They enable innovative approaches to explore gene function and disease mechanisms, ultimately contributing to improved therapeutic strategies. Our company is committed to providing high-quality biological products, backed by extensive expertise in genetic engineering, ensuring that our customers have access to the most reliable tools for their research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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