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ZMYND8 Knockout Cell Lines

Gene: ZMYND8

Official Full Name: zinc finger MYND-type containing 8provided by HGNC

Gene Summary: The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29057 ZMYND8 Knockout cell line (HeLa) Human ZMYND8 1:3~1:6 Negative Online Inquiry
KO29058 ZMYND8 Knockout cell line (HCT 116) Human ZMYND8 1:2~1:4 Negative Online Inquiry
KO29059 ZMYND8 Knockout cell line (HEK293) Human ZMYND8 1:3~1:6 Negative Online Inquiry
KO29060 ZMYND8 Knockout cell line (A549) Human ZMYND8 1:3~1:4 Negative Online Inquiry

Background

ZMYND8 Gene Knockout Cell Lines are specialized cellular models engineered to lack the functional ZMYND8 gene, which encodes a protein implicated in chromatin remodeling and transcriptional regulation. This genetic alteration is achieved through advanced CRISPR-Cas9 technology, enabling precise editing of the genome to create knockout lines that serve as vital tools for elucidating the biological roles of ZMYND8 in various cellular processes.

The primary function of ZMYND8 is its involvement in the epigenetic regulation of gene expression, influencing processes related to cell proliferation, differentiation, and response to DNA damage. By utilizing these knockout cell lines, researchers can investigate how the absence of ZMYND8 affects cellular behavior, gene expression profiles, and signaling pathways, thus advancing our understanding of its contributions to diseases such as cancer and neurodegenerative disorders.

The scientific importance of ZMYND8 Gene Knockout Cell Lines extends to both academic research and clinical applications. They provide a robust platform for drug screening, target validation, and mechanistic studies that contribute to the development of novel therapeutic strategies. In particular, their use can facilitate the identification of potential therapeutic targets in cancer where ZMYND8 activity may be dysregulated.

One of the key advantages of our ZMYND8 Gene Knockout Cell Lines is the high efficiency and specificity of CRISPR-based genome editing, which ensures reproducibility and reliability in research findings. Additionally, our cell lines are rigorously characterized and validated, providing confidence in their use compared to alternative models that may exhibit variability in genetic background or expression profiles.

For researchers and clinicians, the value of ZMYND8 Gene Knockout Cell Lines lies in their ability to streamline experimental workflows, generate high-quality data, and aid in the translation of basic scientific discoveries into clinical applications. Moreover, as leaders in the biological products field, our company is committed to providing state-of-the-art solutions that enhance research capabilities, backed by extensive expertise and a dedication to quality that ensures every product meets the highest standards in scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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