Gene: ZHX3
Official Full Name: zinc fingers and homeoboxes 3provided by HGNC
Gene Summary: This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29932 | ZHX3 Knockout cell line (HeLa) | Human | ZHX3 | 1:3~1:6 | Negative | Online Inquiry |
KO29933 | ZHX3 Knockout cell line (HCT 116) | Human | ZHX3 | 1:2~1:4 | Negative | Online Inquiry |
KO29934 | ZHX3 Knockout cell line (HEK293) | Human | ZHX3 | 1:3~1:6 | Negative | Online Inquiry |
KO29935 | ZHX3 Knockout cell line (A549) | Human | ZHX3 | 1:3~1:4 | Negative | Online Inquiry |
ZHX3 Gene Knockout Cell Lines represent a cutting-edge tool designed for researchers aiming to elucidate the biological roles and molecular mechanisms associated with the ZHX3 gene. These cell lines are engineered using advanced CRISPR-Cas9 technology, which allows for precise editing of the ZHX3 gene, effectively generating models that lack this specific gene's expression. As a consequence, researchers can gain profound insights into the involvement of ZHX3 in various cellular processes, including transcriptional regulation, cellular metabolism, and apoptosis.
The primary function of these knockout cell lines is to facilitate the study of ZHX3’s contribution to pathophysiological conditions such as cancer and metabolic disorders. By observing the functional outcomes of ZHX3 loss, scientists can deduce its significance in transcriptional networks and its potential interactions with other signaling pathways. Furthermore, these cell lines serve as pivotal tools in drug discovery and development, offering a platform to test therapeutic interventions targeting the associated pathways.
One of the main advantages of ZHX3 Gene Knockout Cell Lines over alternative methods, such as RNA interference or traditional gene editing techniques, lies in their stability and efficiency. CRISPR-mediated knockout ensures a complete loss of gene function, providing more consistent and reliable genetic models. Additionally, our product is subjected to rigorous validation and quality control processes, ensuring that researchers receive high-quality cell lines with confirmed genomic alterations.
Researchers and clinicians will find ZHX3 Gene Knockout Cell Lines invaluable for high-throughput screening applications, functional assays, and mechanistic studies, ultimately leading to advancements in understanding and treating diseases linked to ZHX3 dysregulation. Our company specializes in providing high-quality biological products backed by a team of experienced scientists dedicated to supporting innovative research. With ZHX3 Gene Knockout Cell Lines, you are equipped to drive forward your research with confidence in the tools you are utilizing.
Please note that all services are for research use only. Not intended for any clinical use.
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